ArticleJournal of International Society of Preventive & Community Dentistry
Effect of Fluoride-incorporated Bioactive Glass Toothpaste on Remineralization of Primary Enamel Lesions: An
Article in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Biomimetic Enamel Remineralization in Pediatric Dentistry: From Biological Principles to Clinical Evidence.Cureus · 2026Review
- Effects of Sr/F-bioactive glass nanoparticles on pH, elemental release, dentin remineralisation, and cytotoxicity of 1.1% NaF toothpaste.Biomaterial investigations in dentistry · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: This study aimed to evaluate the enamel remineralization effect of fluoride-incorporated bioactive glass (F-BG) toothpaste on artificial subsurface caries in primary teeth. Materials and Methods: Forty sound primary maxillary incisors were subjected to a demineralizing solution for four days to induce artificial enamel caries. The teeth were randomly divided into four experimental groups ( Results: At depths of 0, 40, and 80 μm, both F-BG toothpaste (Group I) and the 1450 ppm fluoride toothpaste (Group III) demonstrated significantly higher remineralization than the 1000 ppm fluoride toothpaste (Group II) and the control group (Group IV) ( Conclusions: The fluoride-incorporated bioactive glass toothpaste (530 ppm fluoride) demonstrated remineralization effects on enamel comparable to those of the 1450 ppm fluoride toothpaste in terms of both surface and subsurface enamel restoration in primary teeth. Clinically, this suggests that F-BG toothpaste may be a viable alternative for remineralization therapy in pediatric populations, especially in situations where lower fluoride concentrations are preferred for young children. Further long-term studies are needed to assess the clinical durability and efficacy of F-BG toothpaste in caries prevention and management.
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