ArticleJournal of International Society of Preventive & Community Dentistry
The Antimicrobial Activity of Zinc Oxide Nanoparticles incorporated into Alginate Impression Material: An
Article in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aim: In dental clinics, disinfecting alginate impression materials is a critical practice to prevent cross-infection. Recently, zinc oxide nanoparticles (ZnO NPs) have been explored for their potential antimicrobial properties, making them promising additives for dental materials. This study investigates the antimicrobial activity of ZnO NPs incorporated into alginate impression materials and assesses the impact on material flow. The objective of this in vitro study was to evaluate the antibacterial and antifungal efficacy of ZnO NPs when incorporated into alginate impression material and to examine its effect on the material's flow properties. Materials and Methods: Zinc oxide nanoparticles were incorporated into an irreversible hydrocolloid alginate impression material at varying concentrations. The antimicrobial properties were assessed using the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) for antifungal activity against Candida albicans, and the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) for antibacterial activity against Staphylococcus aureus. The well-diffusion test was employed to observe zone inhibition. The flow properties of the modified alginate were evaluated using a standardized flow test. Scanning electron microscopy (SEM) was utilized to observe the morphological characteristics and nanoparticle distribution in the alginate matrix. Data were analyzed using one-way analysis of variance (ANOVA) and Duncan's multiple range test, with a significance level set at Results: The results showed that the MIC for ZnO NPs against Candida albicans was 5% by weight, and the MFC was 10% by weight. For Staphylococcus aureus, the MIC was also 5%, with the MBC at 10%. The incorporation of ZnO NPs resulted in a significant reduction in the flow of the alginate material. SEM images revealed a random distribution of ZnO NPs within the alginate matrix, suggesting uniform incorporation. Conclusion: The incorporation of zinc oxide nanoparticles into alginate impression materials conferred both antibacterial and antifungal properties, with effective antimicrobial activity observed at concentrations as low as 5%. However, the addition of ZnO NPs led to a decrease in the material's flow, which may affect the handling characteristics of the alginate. Clinically, the antimicrobial properties of ZnO NP-enhanced alginate could reduce the risk of cross-contamination in dental settings, but the alteration in flow must be considered when selecting or modifying impression materials for clinical use. Future studies should focus on optimizing the concentration of ZnO NPs to balance antimicrobial efficacy with material performance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.