ReviewJournal of food science and technology2025
Sweet or sour? A review of the Aspartame market landscape, carcinogenicity, and its socioeconomic impact.
Review in Journal of food science and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- Artificial sweeteners and risk of cardiometabolic outcomes and mortality: a systematic review and meta-analysis.Nutrition research and practice · 2026Review
- Analysis of toxicity and mechanisms of aspartame in kidney stones with network toxicology and molecular docking strategy.Scientific reports · 2025Article
- Beyond Sugar: A Holistic Review of Sweeteners and Their Role in Modern Nutrition.Foods (Basel, Switzerland) · 2025Review
- Metagenomics and transcriptomics analysis of aspartame's impact on gut microbiota and glioblastoma progression in a mouse model.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Artificial sweeteners with almost zero calories are in high demand in the food and beverage industries due to an increase in diabetes and obesity cases throughout the globe. They vary in their chemical structures and sweetness intensity. The health concerns linked to the consumption of these additives have always been a matter of heated debate. Aspartame being 200 times sweeter than sucrose is one of the most commonly used artificial sweeteners worldwide, capturing a huge market size. India is projected to be the largest market for such additives in the Asia-Pacific region, with many multinational giants investing in the country. There has been an equal number of researches that support as well as reject this claim in recent years. Several studies on Aspartame and its metabolic by-products like diketopiperazine carcinogenicity and a recent declaration of Aspartame as a possible carcinogen to human beings the International Agency for Research on Cancer (IARC) has put aspartame consumption into reconsideration. This bitterness added to the sweetness of Aspartame is also going to impact the market of aspartame and artificial sweeteners. The review highlights the carcinogenic and other health-deteriorating aspects of aspartame along with the possible socio-economic impact of recent findings on the market. Graphical abstract:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.