Evidence map›Paper›PMID 39867522›Full record

ArticlePerspectives in clinical research

Novel trial designs: Master protocol trials.

Priya Ranganathan, Vishal Deo, C S Pramesh, Mahesh P Parmar

Abstract read
In one paragraph

Article in Perspectives in clinical research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Priya RanganathanDepartment of Anaesthesiology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India.
Vishal DeoIndian Council of Medical Research - National Institute for Research in Digital Health and Data Science, New Delhi, India.
C S PrameshDepartment of Surgical Oncology and Administration, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India.
Mahesh P ParmarMedical Research Council Clinical Trials Unit at UCL, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional trial designs are resource and time-intensive. To accelerate the process of testing new interventions, we now have several novel research trial designs. This article focuses on master protocol trials, which allow several therapies to be tested within a single larger trial.

Indexed as

Adaptive clinical trials as topicclinical trialsresearch design

Identifiers

PMID39867522
PMCPMC11759229

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.