ArticleClinical ophthalmology (Auckland, N.Z.)2025
Corneal Epithelial Thickness Mapping in Healthy Population Corneas Using MS-39 Anterior Segment Optical Coherence Tomography.
Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Review
- Comparison of Corneal Epithelial Thickness Profiles Between Aqueous-Deficient and Evaporative Dry Eye Disease.Journal of clinical medicine · 2026Article
- Anterior Segment Optical Coherence Tomography Epithelial Thickness Mapping for Lesion Delineation in Recurrent Corneal Erosion: A Paired-Method Study.Translational vision science & technology · 2026Article
- Repeatability of Anterior Segment Measurements Using Anterior Segment OCT Combined with Placido Corneal Topography in Dry Eye Patients.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- V-Cornea: A computational model of corneal epithelium homeostasis, injury, and recovery.PLoS computational biology · 2025Article
- Normative distribution of corneal epithelial thickness on 9-mm OCT maps.Frontiers in medicine · 2025Article
- Effect of Age and Gender on Corneal Epithelial Thickness in Refractive Surgery Candidates.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The corneal epithelium is the outermost layer of the cornea. It plays a vital role in both normal and pathological conditions of the eye surface and serves as a protective layer. This study aimed to evaluate corneal epithelial thickness (ET) and create a normative database of corneal ET for pediatric and adult age groups using MS-39 AS-OCT. Patients and Methods: This is a cross-sectional multi-center study conducted among the Saudi population. Results: A total of 268 eyes of 268 patients were analyzed (male 50.7% vs female 49.3%). 53.8% were pediatric age group. Higher mean values of central, paracentral, and peripheral were associated with the adult age group except for superior paracentral, temporal peripheral, and nasal peripheral. Male patients had higher mean values of central, paracentral, and peripheral in each quadrant, except for inferior peripheral. There was a significant correlation between inferior, superior, nasal, and temporal in both paracentral and peripheral. No significant correlations were observed between the spherical equivalent and epithelial thickness map. Conclusion: The study found sex differences, with females generally having lower ET values than males, and older age having higher values than children.
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