ReviewInternational journal of preventive medicine2024
Association of the Effect of Alcohol Consumption on Luteinizing Hormone (LH), Follicle-Stimulating Hormone (FSH), and Testosterone Hormones in Men: A Systematic Review and Meta-Analysis.
Review in International journal of preventive medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Immune-nutritional interactions in endometriosis: current evidence and future perspectives in disease management.Frontiers in immunology · 2026Review
- Alcohol and the endocrine system: A critical review of disruptions, potential mechanisms, and health implications.Alcohol, clinical & experimental research · 2026Review
- Testosterone and Obesity in an Aging Society.Biomolecules · 2025Review
- Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in Ghana.Frontiers in reproductive health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The present study is a systematic review and meta-analysis aiming to investigate the effects of alcohol consumption on male sex hormones in humans. Methods: We conducted searches on PubMed, Scopus, Science Direct, and Google Scholar from June 2020 to June 2022. We included observational studies (cohorts, case-controls, and cross-sectional studies) comparing FSH, LH, or testosterone levels in alcohol consumers versus non-consumers. Subgroup analysis based on alcohol intake levels was conducted to explore potential heterogeneity sources. The meta-analysis was done by STATA version 11. Seventeen studies met the criteria. Results: Combining data from these studies, the standardized mean differences for FSH, LH, and testosterone in alcohol-exposed versus non-exposed groups were -0.00 (95% CI: -0.099-0.099), 0.04 (95% CI: 0.00-0.12), and 0.03 (95% CI: -0.11-0.16), respectively, showing no statistical significance. Subgroup analysis indicated a significant difference in FSH levels between moderate/high and low alcohol consumption groups (-0.04, 95% CI: -0.08 to -0.00). Similarly, compared to non-exposed individuals, testosterone levels differed significantly in groups with moderate (0.22, 95% CI: 0.12-0.32) and low (0.19, 95% CI: 0.04-0.35) alcohol intake. Given the notable alterations observed in testosterone levels among individuals with alcohol use disorder and the associated feedback changes in LH levels, it has been concluded that alcohol overuse should be recognized as a factor with destructive effects. Conclusions: It is suggested that future research includes comprehensive studies to investigate the changes in the hypothalamus-pituitary-testis axis induced by alcohol consumption.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.