Evidence map›Paper›PMID 39867227›Full record

ArticleFrontiers in physiology2024

Stellate ganglion blockade under ultrasound-guidance and the physiological responses in the rat.

Robert M N Tran, Shaista Malik, Christopher Reist, Chad K Oh, Najeebah Abdul-Musawir, Stephanie C Tjen-A-Looi, Liang-Wu Fu, Theodore J Baird, Anh T Nguyen, Yiwei D Gong and 1 more

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Article in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Robert M N TranSusan Samueli Integrative Health Institute and Department of Medicine, University of California, Irvine, Irvine, CA, United States.
Shaista MalikSusan Samueli Integrative Health Institute and Department of Medicine, University of California, Irvine, Irvine, CA, United States.
Christopher ReistAEON Biopharma, Inc., Irvine, CA, United States.
Chad K OhAEON Biopharma, Inc., Irvine, CA, United States.
Najeebah Abdul-MusawirAEON Biopharma, Inc., Irvine, CA, United States.
Stephanie C Tjen-A-LooiSusan Samueli Integrative Health Institute and Department of Medicine, University of California, Irvine, Irvine, CA, United States.
Liang-Wu FuSusan Samueli Integrative Health Institute and Department of Medicine, University of California, Irvine, Irvine, CA, United States.
Theodore J BairdAEON Biopharma, Inc., Irvine, CA, United States.
Anh T NguyenSusan Samueli Integrative Health Institute and Department of Medicine, University of California, Irvine, Irvine, CA, United States.
Yiwei D GongSusan Samueli Integrative Health Institute and Department of Medicine, University of California, Irvine, Irvine, CA, United States.
Zhi-Ling GuoSusan Samueli Integrative Health Institute and Department of Medicine, University of California, Irvine, Irvine, CA, United States.

Funding

Neuroimmune mechanisms underlying electroacupuncture effect on vascular functionR01AT011306 · NCCIH · UNIVERSITY OF CALIFORNIA-IRVINE · PI MALIK, SHAISTA, TJEN-A-LOOI, STEPHANIE CHEE-YEE · 2021 to 2025
$3.1M
NCCIH NIH HHS R01 AT011306
6 · The paper itself

Abstract

Stellate ganglion blockade (SGB) is a practical approach to managing many clinical disorders. Ultrasound-guided SGB is currently adopted as a more effective and safer method in humans. Developing this technique in rats would facilitate further study of SGB application. The present study examined physiological responses following ultrasound-guided SGB in Sprague-Dawley rats. Under general anesthesia, lidocaine containing Chicago blue dye (1.0%-1.5% in 40-60 µL) was injected into the unilateral stellate ganglion (SG). Ptosis was observed on the ipsilateral right (n = 8) or left (n = 7) side of lidocaine administration. No ptosis was noted in any controls by 0.9% normal saline injection into the right (n = 6) or left (n = 6) SG. Heart rate (HR) was significantly decreased after administration of lidocaine (344 ± 32 to 289 ± 47 bpm;

Indexed as

autonomic nervous systemheartlidocaineratstellate ganglionultrasound

Identifiers

PMID39867227
PMCPMC11757301

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.