Evidence map›Paper›PMID 39867194›Full record

ReviewReviews in cardiovascular medicine2025

Association of Insomnia, Lipid Profile, and Lipid-Lowering Medications: A Narrative Review.

Fang Jia, Shun-Yi Shi, Si-Fan Fei, Min Zhou, Jian-Jun Li

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fang JiaDepartment of Cardiology, The Third Affiliated Hospital of Soochow University, 213003 Changzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-6828-2847
Shun-Yi ShiDepartment of Cardiology, The Third Affiliated Hospital of Soochow University, 213003 Changzhou, Jiangsu, China.ORCID https://orcid.org/0000-0002-5205-1817
Si-Fan FeiDepartment of Cardiology, The Third Affiliated Hospital of Soochow University, 213003 Changzhou, Jiangsu, China.ORCID https://orcid.org/0009-0008-9319-2596
Min ZhouDepartment of Cardiology, The Third Affiliated Hospital of Soochow University, 213003 Changzhou, Jiangsu, China.ORCID https://orcid.org/0009-0005-5865-5303
Jian-Jun LiCardio-Metabolic Center, Fu Wai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, 10037 Beijing, China.ORCID https://orcid.org/0000-0003-2536-4364

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep is a fundamental phenomenon that helps maintain normal physiological processes. Conversely, sleep disorders, usually presented as insomnia, are a common public health problem that can lead to multiple pathophysiological changes in humans, including lipid metabolic abnormality. Interestingly, several previous studies have examined the potential relation of insomnia to metabolic syndrome and hyperlipidemia and found that insomnia was associated with elevated plasma cholesterol and triglyceride concentrations. This review summarizes evidence regarding the linkage between insomnia and lipid abnormalities. Moreover, the underlying physiologic mechanisms linking insomnia to lipid abnormalities are systemically discussed. Finally, issues with lipid-lowering drugs and the risk of insomnia are also presented. This knowledge can improve our understanding of the pathophysiological features of insomnia, which may help to prevent and treat insomnia-induced dyslipidemia clinically.

Indexed as

coronary artery diseaseinsomnialipid metabolismproprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i)statin

Identifiers

PMID39867194
PMCPMC11759977

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.