ArticleCureus2024
The Impact of Thyroid Hormone Imbalance on Cardiovascular Health: A Population-Based Study.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cardiac electrical remodeling in Graves' disease: insights from global ventricular repolarization indices.Frontiers in endocrinology · 2026Observational
- Case Report: Generalized anxiety disorder and hypertension: a bidirectional loop unraveled by integrated management.Frontiers in psychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThyroid hormone imbalances are known to significantly affect cardiovascular health, contributing to conditions such as arrhythmias, dyslipidemia, and hypertension. Given the increasing prevalence of thyroid dysfunction and its potential impact on cardiovascular outcomes, early diagnosis and intervention are crucial, particularly within specific regional populations.
objectiveThis study aimed to evaluate the impact of thyroid hormone imbalance on cardiovascular health outcomes in patients at Lady Reading Hospital, Peshawar, over a 24-month period. MATERIALS AND
methodsA prospective cohort study was conducted between October 2022 and September 2024, involving 150 adult patients diagnosed with thyroid dysfunction, categorized into subclinical, hyperthyroid, and hypothyroid groups. The study assessed key cardiovascular health indicators, including blood pressure, lipid profiles, heart rate, and electrocardiograms (ECGs), at baseline and during follow-up visits at 6, 12, and 24 months. Participants were included if they met the biochemical criteria for thyroid dysfunction and had no significant pre-existing cardiovascular disease. Data were collected through medical records and standardized questionnaires. The Institutional Review Board at Lady Reading Hospital approved the study.
resultsDyslipidemia was found in 90 participants (60%), hypertension in 99 participants (66%), and hypothyroidism in 76 participants (72%). Arrhythmias were observed in 14 individuals (46%) with hyperthyroidism. ECG findings revealed sinus bradycardia in 32 participants (30%) with hypothyroidism and sinus tachycardia in 23 participants (76%) with hyperthyroidism. Multivariate analysis showed that hypothyroidism significantly increased the odds of hypertension (OR = 3.2, p = 0.001), dyslipidemia (OR = 2.9, p = 0.003), and arrhythmias (OR = 4.3, p < 0.001).
conclusionThyroid hormone imbalance has a profound impact on cardiovascular health, with hyperthyroidism linked to arrhythmias and hypothyroidism associated with hypertension and dyslipidemia. Subclinical thyroid dysfunction also increases cardiovascular risks, emphasizing the need for early detection and region-specific management strategies. This study provides valuable insights into the long-term cardiovascular effects of thyroid dysfunction in the Khyber Pakhtunkhwa (KPK) region, supporting the importance of routine screening and timely intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.