ArticleCureus2024
Factors Associated With the Severity of Diabetic Ketoacidosis on Admission in Pediatric Intensive Care: A Retrospective Study.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Diabetic ketoacidosis (DKA) is one of the leading causes of morbidity and mortality in children with diabetes, often requiring intensive care unit management. This study aimed to identify factors associated with the severity of DKA in infants and children hospitalized in pediatric intensive care. Methodology This retrospective, monocentric, descriptive, analytical study included infants and children aged one month to 17 years who presented with DKA meeting the International Society for Pediatric and Adolescent Diabetes 2022 criteria. The study was conducted at the Pediatric Intensive Care Unit of the International University Hospital Cheikh Khalifa in Casablanca from July 2018 to February 2023. For data analysis, patients were divided into two groups, namely, severe DKA and non-severe DKA. Data analysis was performed using Jamovi software. Results Of the 63 children included, 26 (41.3%) had severe DKA, and 37 (58.7%) had non-severe DKA. The mean age was 8.92 ± 5.18 years, with a sex ratio of 0.97. Statistical analysis revealed a significant clinical difference between DKA severity and the presence of dyspnea at admission (p = 0.004) and drowsiness (p = 0.003). Regarding biological parameters, the study showed that patients with severe DKA had significantly higher white blood cell (WBC) counts (p = 0.013), as well as significantly higher procalcitonin (PCT) levels (p = 0.038) and C-reactive protein (CRP) concentrations (p = 0.011) compared to children admitted with non-severe DKA. No significant differences were observed between the two groups regarding age, sex, symptoms, triggering factors, or clinical outcomes. Conclusions The severity of DKA in children is associated with the presence of neurological disturbances and dyspnea at admission, as well as a significant elevation in WBC count, CRP, and PCT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.