Evidence map›Paper›PMID 39867002›Full record

ArticleCureus2024

Multidisciplinary Approaches and Molecular Diagnostics in New-Onset Refractory Status Epilepticus and Nontuberculous Mycobacterial CNS Infections in the ICU: A Case Report.

Pedro Manuel Batarda Sena, Margarida Ferro, Joana Alves Cabrita, Carlos Pontinha, Ana Mestre, Mário Oliveira, Luis Bento

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. ChronicInfection and drug resistance · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pedro Manuel Batarda SenaIntensive Care Department, Hospital Central do Funchal, Funchal, PRT.
Margarida FerroNeurology Department, Hospital de S. José, Unidade Local de Saúde de São José, Lisbon, PRT.
Joana Alves CabritaIntensive Care Unit, Unidade Local de Saúde de São José, Lisbon, PRT.
Carlos PontinhaPathology and Laboratory Medicine Department, Unidade Local de Saúde de São José, Lisbon, PRT.
Ana MestreInternal Medicine Department, Hospital Distrital de Santarém, Santarém, PRT.
Mário OliveiraPathology and Laboratory Medicine Department, Unidade Local de Saúde de São José, Lisbon, PRT.
Luis BentoMedical Emergency Unit, Unidade Local de Saúde de São José, Lisbon, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis and management of complex neurological conditions such as New-Onset Refractory Status Epilepticus (NORSE) and central nervous system (CNS) infections caused by non-tuberculous mycobacteria (NTM) pose substantial difficulties in intensive care units (ICUs). This article combines a case report and a literature review that explores the diagnostic dilemmas and therapeutic strategies for these critical conditions. We report the case of an 83-year-old female with chronic granulomatous meningitis secondary to NTM, presenting a challenging diagnostic and complex management complexity typical of such a rare disease through a period time of five years. Her case emphasized the importance of a multidisciplinary approach in such cases, as the interplay between neurology and intensive care was vital. The need for new molecular diagnostic technologies is shown to be of high significance in identifying the causative pathogens and improving patient outcomes in these rare but critical conditions.

Indexed as

central nervous systemcentral nervous system infectionsdiagnostic toolsgranulomatous meningitisintensive careintensive care unitmolecular diagnosticsmolecular diagnostics multidisciplinary management granulomatous meningitis next-generation sequencingnew-onset refractory status epilepticusnontuberculous mycobacterial infections

Identifiers

PMID39867002
PMCPMC11763716

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.