Evidence map›Paper›PMID 39866989›Full record

ArticleCureus2024

Varied Clinical Features and Outcomes of Autoimmune Encephalitis: A Retrospective Case Series.

Aruna Kumari Kotteti, Elanthiraiyan Govindaswamy Chelvakumar, Robert Wilson Sundaram, Kalpana Radhakrishnan, Arunan Subbiah

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aruna Kumari KottetiNeurology, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Chengalpattu, IND.
Elanthiraiyan Govindaswamy ChelvakumarNeurology, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Chengalpattu, IND.
Robert Wilson SundaramNeurology, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Chengalpattu, IND.
Kalpana RadhakrishnanNeurology, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Chengalpattu, IND.
Arunan SubbiahNeurology, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Chengalpattu, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study discusses the various clinical profiles, investigatory findings, treatment responses, and prognosticating factors in seven cases of autoimmune encephalitis (AE).

methodsThe clinical records of seven AE patients admitted to the Neurology Department, SRM Medical College Hospital and Research Centre, Chennai, from July 2022 to December 2023 were retrospectively analyzed.

resultsThe patients' ages ranged from 18 to 35, and all experienced seizures. Only two patients exhibited cognitive decline and psychiatric problems. All seven cases were clinically diagnosed as AE: three were positive for anti-N-methyl-D-aspartate receptor (anti-NMDAR) antibodies, while the AE panel was negative in the remaining patients. In all cases, contrast imaging of the brain on MRI appeared normal.

conclusionPatients with AE need to be diagnosed early because prompt immunosuppressive therapy effectively reduces morbidity and mortality. A detailed history, clinical examinations, and relevant investigations are required. Mild and atypical forms with negative autoimmune antibody panels with relatively good outcomes are increasingly encountered.

Indexed as

anti-gamma aminobutyric acid receptor antibodiesanti hu(antineuronal nuclear antibody-type 1)anti ma(neuronal antibody or purkinje cell antibody)anti n-methyl-d-aspartate receptor antibodiesautoimmune encephalitiscognitive declinecontactin-associated protein-like 2leucine-rich glioma-inactivated 1 (lgi1) antibodyα-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor

Identifiers

PMID39866989
PMCPMC11762242

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