Evidence map›Paper›PMID 39866948›Full record

ArticleEJHaem2025

The long-term risk of immune-related conditions in survivors of diffuse large B-cell lymphoma: A Danish nationwide registry study.

Laura Schou Pedersen, Nadja Nørholm Klausen, Jonas Faartoft Jensen, Emilis Danielsen Bacevičius, Peter Brown, Judit Mészáros Jørgensen, Thomas Stauffer Larsen, Christian Bjørn Poulsen, Michael Roost Clausen, Robert Schou Pedersen and 6 more

Abstract read
In one paragraph

Article in EJHaem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Laura Schou PedersenDepartment of Haematology, Clinical Cancer Research Center Aalborg University Hospital Aalborg Denmark.
Nadja Nørholm KlausenDepartment of Haematology, Clinical Cancer Research Center Aalborg University Hospital Aalborg Denmark.
Jonas Faartoft JensenDepartment of Haematology, Clinical Cancer Research Center Aalborg University Hospital Aalborg Denmark.ORCID https://orcid.org/0009-0000-1006-4751
Emilis Danielsen BacevičiusDepartment of Haematology, Clinical Cancer Research Center Aalborg University Hospital Aalborg Denmark.
Peter BrownDepartment of Haematology Rigshospitalet Copenhagen Denmark.
Judit Mészáros JørgensenDepartment of Haematology Aarhus University Hospital Aarhus Denmark.
Thomas Stauffer LarsenDepartment of Haematology Odense University Hospital Odense Denmark.ORCID https://orcid.org/0000-0002-8418-6708
Christian Bjørn PoulsenDepartment of Haematology Zealand University Hospital Roskilde Denmark.
Michael Roost ClausenDepartment of Haematology Vejle Sygehus Vejle Denmark.
Robert Schou PedersenDepartment of Medicine Gødstrup sygehus Herning Denmark.
Anne Ortved GangDepartment of Haematology Rigshospitalet Copenhagen Denmark.
Rasmus WestermannDepartment of Rheumatology Center of Rheumatic Research Aalborg (CERRA) Aalborg University Hospital Aalborg Denmark.
Salome KristensenDepartment of Rheumatology Center of Rheumatic Research Aalborg (CERRA) Aalborg University Hospital Aalborg Denmark.
Lene Wohlfahrt DreyerDepartment of Rheumatology Center of Rheumatic Research Aalborg (CERRA) Aalborg University Hospital Aalborg Denmark.
Tarec Christoffer El-GalalyDepartment of Haematology Aarhus University Hospital Aarhus Denmark.
Lasse Hjort JakobsenDepartment of Haematology, Clinical Cancer Research Center Aalborg University Hospital Aalborg Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is limited knowledge of the long-term effects on the immune system after treatment for diffuse large B-cell lymphoma (DLBCL). Methods: This study included DLBCL patients from the Danish Lymphoma Registry who obtained complete remission (CR) after (R)-CHOP (cyclophosphamide, doxorubicin, vincristine, prednisolone)-like immunochemotherapy. Each R Results: R Conclusion: R-CHOP-like treated patients face an increased risk of infections and AC-IDs overall compared with the background population. The risk of infections and AC-IDs did not change overall after the addition of rituximab to CHOP, however, an increased risk of respiratory infections is notable. These findings could highlight the need for expanded vigilance and prophylaxis strategies.

Indexed as

autoimmune conditionsdiffuse large B‐cell lymphomaimmune deficienciesimmunochemotherapyinfections

Identifiers

PMID39866948
PMCPMC11756995

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.