Evidence map›Paper›PMID 39866880›Full record

ArticleResearch square2025

Electrochemical DABCOylation enables challenging aromatic C-H amination.

Christian Malapit, Griffin Stewart, Eva Maria Alvarez, Chris Rapala, Jonathan Sklar, Julia Kalow

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Christian MalapitNorthwestern University.ORCID 0000-0002-8471-4208
Griffin StewartNorthwestern University.
Eva Maria AlvarezNorthwestern University.
Chris RapalaNorthwestern University.
Jonathan SklarNorthwestern University.
Julia KalowNorthwestern University.ORCID 0000-0002-4449-9566

Funding

Electrocatalysis for the synthesis of chiral and PET imaging pharmaceuticalsR00GM140249 · NIGMS · NORTHWESTERN UNIVERSITY · PI MALAPIT, CHRISTIAN · 2022 to 2024
$747k
NIGMS NIH HHS R00 GM140249
6 · The paper itself

Abstract

The selective amination of aromatic C-H bonds is a powerful strategy to access aryl amines, functionalities found in many pharmaceuticals and agrochemicals. Despite advances in the field, a platform for the direct, selective C-H amination of electronically diverse (hetero)arenes, particularly electron-deficient (hetero)arenes, remains an unaddressed fundamental challenge.

Identifiers

PMID39866880
PMCPMC11760240

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.