ArticleMaterials today. Bio2025
3D printing of biological tooth with multiple ordered hierarchical structures.
Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Enamel-inspired composite with robust mechanical properties and self-healing capability.Nature communications · 2026Article
- Multiscale Design of Dental Restorative Materials: Mechanistic Foundations, Technological Innovations, and Clinical Translation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural teeth fulfill functional demands by their heterogeneity. The composition and hydroxyapatite (HAp) nanostructured orientation of enamel differ from those of dentin. However, mimicking analogous materials still exhibit a significant challenge. Herein, a bottom-up, sequential approach was formulated by combining shear-induced and magnetic-assisted 3D printing technology, enabling the fabrication of the intricate microstructure of a multi-material dental crown, where the HAp nanostructure is highly ordered and almost perpendicular to each other at the dentinoenamel junction (DEJ). The HAp nanorods were first induced to achieve high orientation in each printed line, then formed a plane with a vertical structure of DEJ under the shear force and magnetic field at dentin and enamel, respectively, and finally 3D-printed into a dental crown with bilayered parts exhibiting site-specific composition, texture, and outstanding biocompatibility. This novel approach can be applied to design and fabricate natural tooth crowns, indicating the potential for multi-level and multi-dimensional texture control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.