Evidence map›Paper›PMID 39866788›Full record

ArticleMaterials today. Bio2025

Tailored biomimetic nanoreactor improves glioma chemodynamic treatment via triple glutathione depletion and prompt acidity elevation.

Ya Wen, Qiansai Qiu, Feng Feng, Yujuan Zhu, Jianquan Zhang, Zesheng Sun, Tuodi Zhang, Wei Shi, Jinlong Shi

Abstract read
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. A pH/HInternational journal of nanomedicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ya WenDepartment of Neurosurgery, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
Qiansai QiuDepartment of Radiology, Tumor Hospital Affiliated to Nantong University, Nantong, 226001, China.
Feng FengDepartment of Radiology, Tumor Hospital Affiliated to Nantong University, Nantong, 226001, China.
Yujuan ZhuDepartment of Neurosurgery, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
Jianquan ZhangDepartment of Radiology, Tumor Hospital Affiliated to Nantong University, Nantong, 226001, China.
Zesheng SunDepartment of Neurosurgery, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
Tuodi ZhangDepartment of Neurosurgery, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
Wei ShiDepartment of Neurosurgery, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
Jinlong ShiDepartment of Neurosurgery, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemodynamic therapy (CDT) is an emerging antitumor strategy utilizing iron-initiated Fenton reaction to destroy tumor cells by converting endogenous H

Indexed as

Acidity elevationBiomimetic nanoreactorChemodynamic therapyGliomaGSH exhaustion

Identifiers

PMID39866788
PMCPMC11762625

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.