Evidence map›Paper›PMID 39866648›Full record

ArticleWorld journal of clinical cases2025

Irreversible electroporation for metastatic pancreatic carcinoma with liver metastasis: What does the evidence say.

Ranit Seal, Akash Bararia, Bitan Kumar Chattopadhyay, Nilabja Sikdar

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ranit SealDepartment of General Surgery, IPGME & R and SSKM Hospital, Kolkata 700020, West Bengal, India.
Akash BarariaHuman Genetics Unit, Indian Statistical Institute, Kolkata 700108, West Bengal, India.
Bitan Kumar ChattopadhyayDepartment of General Surgery, IPGME & R and SSKM Hospital, Kolkata 700020, West Bengal, India.
Nilabja SikdarHuman Genetics Unit, Indian Statistical Institute, Kolkata 700108, West Bengal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irreversible electroporation is a promising non-thermal ablation method that has been shown to increase overall survival in locally advanced pancreatic cancer in some studies. However, higher quality studies with proper controls and randomization are required to establish its superiority when added with neoadjuvant chemotherapy over the current management of choice, which is chemotherapy alone. Further studies are required before establishment of any survival benefit in metastatic pancreatic carcinoma, and such evidence is lacking at present.

Indexed as

Advanced pancreatic carcinomaChemotherapyIrreversible electroporationLocally advanced pancreatic carcinomaMetastatic pancreatic carcinoma

Identifiers

PMID39866648
PMCPMC11577528

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.