Evidence map›Paper›PMID 39866641›Full record

ArticleInternational journal of nephrology and renovascular disease2025

Correlation Between the Inferior Vena Cava/Aorta (Ivc/Ao) Ratio and Serum Lactate Levels in Children With Renal Disorder.

Dzulfikar Djalil Lukmanul Hakim, Ahmedz Widiasta, Dedi Rachmadi, Sri Endah Rahayunigsih, Putria Rayani Apandi, Riyadi Adrizain, Muhamad Rinaldhi Akbar Martiano

Abstract read
In one paragraph

Article in International journal of nephrology and renovascular disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dzulfikar Djalil Lukmanul HakimDivision of Emergency and Intensive Care, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran Dr. Hasan Sadikin, Bandung, Indonesia.
Ahmedz WidiastaDivision of Nephrology, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran Dr. Hasan Sadikin, Bandung, Indonesia.ORCID 0000-0001-5664-089X
Dedi RachmadiDivision of Nephrology, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran Dr. Hasan Sadikin, Bandung, Indonesia.
Sri Endah RahayunigsihDivision of Cardiology, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran Dr. Hasan Sadikin, Bandung, Indonesia.
Putria Rayani ApandiDivision of Cardiology, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran Dr. Hasan Sadikin, Bandung, Indonesia.
Riyadi AdrizainDivision of Infection, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran Dr. Hasan, Sadikin, Bandung, Indonesia.
Muhamad Rinaldhi Akbar MartianoDepartment of Pediatric, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute kidney injury (AKI) is common in critically ill children in the PICU, with incidence rates from 2.5% to 58%, impacting mortality and hospital duration. Early AKI detection is vital, but conventional hemodynamic monitoring often lacks specificity. This study investigates the relationship between the inferior vena cava/aortic (IVC/Ao) ratio and serum lactate levels as non-invasive indicators of renal hemodynamics and tissue perfusion in children. Understanding these parameters could improve early diagnosis, aid clinical decisions, and enhance outcomes for pediatric AKI patients, offering an accessible monitoring method for clinicians. Methods: This cross-sectional study involved 48 pediatric patients aged 5-18 years showing Pediatric Early Warning Score (PEWS) ≥3 and diagnosed with renal disorders. Patients were admitted to the emergency department, high care unit, PICU, and pediatric ward at Dr. Hasan Sadikin Hospital, Bandung, between May and August 2023. AKI was diagnosed using pRIFLE or KDIGO criteria. The IVC/Ao ratio was assessed via transabdominal USG, and serum lactate levels were measured. Spearman correlation analysis was conducted to assess their relationship. Results: The median (IQR) IVC/Ao ratio was 0.91 (0.70-1.10), and serum lactate levels were 1.5 (1.1-2.4) mmol/L. Spearman correlation analysis revealed a negative correlation between the IVC/Ao ratio and serum lactate (rho = -0.65, p < 0.001). Conclusion: A decrease in the IVC/Ao ratio correlates with an increase in serum lactate levels in children with AKI.

Indexed as

acute kidney injurychildrenIVC/Aoserum lactate

Identifiers

PMID39866641
PMCPMC11766292

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.