Evidence map›Paper›PMID 39866623›Full record

ArticleACS omega2025

Novel D-Ribofuranosyl Tetrazoles: Synthesis, Characterization, In Vitro Antimicrobial Activity, and Computational Studies.

Riham Sghyar, Mouad Lahyaoui, Yassine Rhazi, Noura Aflak, Oussama Moussaoui, Alae Chda, Mohammed M Alanazi, Atul Kabra, El Mestafa El Hadrami, El Houssine Mabrouk and 2 more

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  3. Synthesis of α-Santonin Derivatives Linked toAntibiotics (Basel, Switzerland) · 2026
    Article
  4. Linking phytochemistry to bioactivity:Frontiers in chemistry · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Riham SghyarLaboratory of Applied Organic Chemistry, Université Sidi Mohamed Ben Abdellah, Faculté des Sciences et Techniques de Fès, B.P. 2202, Routed 'Imouzzer, Fez 30050, Morocco.
Mouad LahyaouiLaboratory of Applied Organic Chemistry, Université Sidi Mohamed Ben Abdellah, Faculté des Sciences et Techniques de Fès, B.P. 2202, Routed 'Imouzzer, Fez 30050, Morocco.ORCID https://orcid.org/0000-0002-8068-7177
Yassine RhaziLaboratory of Engineering, Organometallic, Molecular and Environment (LIMOME), Université Sidi Mohamed Ben Abdellah, Faculté des Sciences Dhar El Mahraz, Fez 30003, Morocco.
Noura AflakLaboratory of Analytical and Molecular Chemistry/LCAM, Université Cadi Ayyad, Faculté Polydisciplinaire de SAFI, Safi 46030, Morocco.ORCID https://orcid.org/0000-0002-6396-2114
Oussama MoussaouiLaboratory of Applied Organic Chemistry, Université Sidi Mohamed Ben Abdellah, Faculté des Sciences et Techniques de Fès, B.P. 2202, Routed 'Imouzzer, Fez 30050, Morocco.
Alae ChdaInstitut Supérieur Des Professions Infirmières Et Techniques de Santé, Fes 30050, Morocco.
Mohammed M AlanaziDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Atul KabraUniversity Institute of Pharma Sciences, Chandigarh University, Mohali, Punjab 140413, India.
El Mestafa El HadramiLaboratory of Applied Organic Chemistry, Université Sidi Mohamed Ben Abdellah, Faculté des Sciences et Techniques de Fès, B.P. 2202, Routed 'Imouzzer, Fez 30050, Morocco.
El Houssine MabroukLaboratory of Engineering, Organometallic, Molecular and Environment (LIMOME), Université Sidi Mohamed Ben Abdellah, Faculté des Sciences Dhar El Mahraz, Fez 30003, Morocco.
El Hassane AnouarDepartment of Chemistry, College of Science and Humanities, Prince Sattam Bin Abdulaziz University, Al-Kharj 16242, Saudi Arabia.
Nada Kheira SebbarApplied Chemistry and Environment Laboratory, Applied Bioorganic Chemistry Team, Faculty of Science, Ibn Zohr University, Agadir 80000, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of this study was to synthesize and evaluate new antimicrobial compounds. We specifically focused on the development of 2,5-disubstituted tetrazole derivatives containing the O-methyl-2,3-O-isopropylidene-(D)-ribofuranoside groups through N-alkylation reactions. The synthesized compounds were characterized using

Identifiers

PMID39866623
PMCPMC11755160

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.