Evidence map›Paper›PMID 39866622›Full record

ArticleACS omega2025

Transient Expression of Zika NS2B Protein Antigen in

Mario A M Herazo, Daylana R S Dantas, Bruno B Silva, Helen P S Costa, Eduarda N F N Santos, Luiz F W G Moura, João X S Neto, Maurício F Van Tilburg, Eridan O P T Florean, Arlindo A Moura and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mario A M HerazoLaboratory of Biotechnology and Molecular Biology, Health Sciences Center, State University of Ceara, Fortaleza 60714-903, Brazil.
Daylana R S DantasLaboratory of Biotechnology and Molecular Biology, Health Sciences Center, State University of Ceara, Fortaleza 60714-903, Brazil.
Bruno B SilvaLaboratory of Biotechnology and Molecular Biology, Health Sciences Center, State University of Ceara, Fortaleza 60714-903, Brazil.
Helen P S CostaLaboratory of Biotechnology and Molecular Biology, Health Sciences Center, State University of Ceara, Fortaleza 60714-903, Brazil.
Eduarda N F N SantosLaboratory of Biotechnology and Molecular Biology, Health Sciences Center, State University of Ceara, Fortaleza 60714-903, Brazil.
Luiz F W G MouraLaboratory of Biotechnology and Molecular Biology, Health Sciences Center, State University of Ceara, Fortaleza 60714-903, Brazil.
João X S NetoLaboratory of Biotechnology and Molecular Biology, Health Sciences Center, State University of Ceara, Fortaleza 60714-903, Brazil.
Maurício F Van TilburgLaboratory of Biotechnology and Molecular Biology, Health Sciences Center, State University of Ceara, Fortaleza 60714-903, Brazil.
Eridan O P T FloreanLaboratory of Biotechnology and Molecular Biology, Health Sciences Center, State University of Ceara, Fortaleza 60714-903, Brazil.
Arlindo A MouraFederal University of Ceara, Fortaleza 60355-636, Brazil.ORCID https://orcid.org/0000-0002-8271-5733
Maria I F GuedesLaboratory of Biotechnology and Molecular Biology, Health Sciences Center, State University of Ceara, Fortaleza 60714-903, Brazil.ORCID https://orcid.org/0000-0002-4569-8663

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zika (ZIKV) and Dengue (DENV) viruses are clinically significant due to their severe neurological and hemorrhagic complications. Rapid diagnostics often rely on nonstructural proteins to generate specific antibodies. This study aimed to produce IgG antibodies from the recombinant ZIKV protein and plant-expressed NS2B protein for arbovirus detection in serum and urine samples. The NS2B protein was expressed in

Identifiers

PMID39866622
PMCPMC11755152

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.