Evidence map›Paper›PMID 39866571›Full record

ArticlePeerJ2025

The bacterial composition signatures of perianal abscess and origin of infecting microbes.

Song Han, Wenya Su, Kefeng Fan, Zhen Xu, Hai Xu, Mingyu Wang, Ling Li, Wenlong Shen

Abstract read
In one paragraph

Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Association Between Diabetes Mellitus and Perianal Abscess: A Meta-Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Song Han *Department of Anorectal Surgery, Cheeloo College of Medicine, Qilu Hospital (Qingdao), Qingdao, China.
Wenya Su *State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University (Qingdao), Qingdao, Shandong, China.
Kefeng FanDepartment of Respiratory Diseases, Qingdao Chengyang District People's Hospital, Qingdao, China.
Zhen XuDepartment of Anorectal Surgery, Cheeloo College of Medicine, Qilu Hospital (Qingdao), Qingdao, China.
Hai XuState Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University (Qingdao), Qingdao, Shandong, China.
Mingyu WangState Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University (Qingdao), Qingdao, Shandong, China.ORCID 0000-0003-1215-9556
Ling LiState Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University (Qingdao), Qingdao, Shandong, China.
Wenlong ShenDepartment of Anorectal Surgery, Cheeloo College of Medicine, Qilu Hospital (Qingdao), Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Perianal abscess is a common anal condition primarily caused by bacterial infections, yet the precise origins of these infecting bacteria remain unclear. Understanding the distinct microbial signatures associated with periaabscesses is crucial for provide fresh ideas for disease prevention. Materials and Methods: Samples of anal skin, feces, and abscesses were collected from a cohort of 75 patients diagnosed with perianal abscesses. The microbial composition at each site was analyzed using 16S rRNA gene sequencing to characterize the bacterial communities present. Results: Analysis using MaAslin2 revealed distinct bacterial compositional signatures among the anal skin, feces, and abscess samples. Alpha diversity analysis indicated significant differences in bacterial diversity between abscesses, anal skin, and feces, with abscesses showing lower diversity compared to higher richness in feces. Biomarker analysis highlighted key taxa such as

Indexed as

AbscessAnal CanalAnus DiseasesBacteriaAdultAgedFecesFemaleHumansMaleMiddle AgedRNA, Ribosomal, 16SSkinRNA, Ribosomal, 16S16S rRNA gene sequencingMicrobial compositionPerianal abscessSource of microbes

Identifiers

PMID39866571
PMCPMC11766672

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.