ArticleHeliyon2025
The strategy to control the outbreak of an emerging respiratory infectious disease in a simulated Chinese megacity.
Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Effect of liver fibrosis on gadolinium retention from gadodiamide, gadobutrol, and gadoxetate disodium in rats.Japanese journal of radiology · 2026Article
- Mechanistic insights into natural product-driven modulation of NLRP3-inflammasome signalling in metabolic syndrome.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Review
- Organoid-based systems for biomedical innovation: advances in disease modeling, drug screening, and precision medicine.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Advancements in Stem Cell Therapy for Managing Drug-Resistant Epilepsy.Molecular neurobiology · 2026Review
- Identification of risk factors and response strategies in interhospital transfer of critically ill patients with respiratory infectious diseases: a qualitative study.Frontiers in public health · 2026Article
- Stem Cell Based Regenerative Applications for the Management of Diabetes Induced Systemic Complications.Stem cell reviews and reports · 2026Review
- Research Advances on the Impact of Gut Microbiota on COPD: Exploring New Perspectives on the Microbiota-Gut-Lung Axis.Current microbiology · 2025Review
- Intermodulation of endoplasmic reticulum stress and ferroptosis in diabetic nephropathy: molecular mechanisms and therapeutic potentials.Apoptosis : an international journal on programmed cell death · 2025Review
- Metagenomics and its impact on environmental and therapeutic microbiology.Archives of microbiology · 2025Review
- Veterinary Regenerative Medicine: The Evolving Role of Stem Cell-Based Therapies.Stem cell reviews and reports · 2025Review
- Frequency-aligned loss and spectral filtering improve long-range influenza forecasting.Frontiers in public health · 2025Article
- Higher BMI and extraversion are associated with greater button-press force in a lab setting.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: The emergence of respiratory infectious diseases (ERID) poses a significant threat to global public health. However, effectively managing ERID outbreaks in large cities remains a challenge. Methods: An age-structured Susceptible-Exposed-Infectious-Removed (SEIR) model was developed to predict the effectiveness of non-pharmaceutical interventions (NPIs) in controlling ERID outbreaks. Four ERID outbreak scenarios were created based on varying levels of infectivity and pathogenicity. Based on the World Health Organization's (WHO) categorization for responding to the influenza pandemic, the combinations of NPIs were classified into five levels: base, any, moderate, high, and extraordinary levels (from mild to severe). The simulated progression of ERID outbreaks in a megacity were compared across different levels of NPI. Results: Our findings indicate that the response strategies should be formulated based on the epidemiological characteristics of ERID. In the low transmission scenarios, the mandatory NPIs were unnecessary to control ERID outbreaks regardless of their pathogenicity. However, even with low pathogenicity, severe NPIs are required to control the spread of ERID and minimize harm to the public in high transmission scenarios. Conclusion: The NPIs for the EIRD outbreak in a city should be tailored to the epidemiological characteristics to control its impact and protect public health.
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