Evidence map›Paper›PMID 39866447›Full record

ArticleHeliyon2025

Evaluation of bone development and organs in rat fetuses exposed to tartrazine.

Osman Öztürk, Sümeyye Uçar, Züleyha Doğanyiğit, Aslı Okan Oflamaz, Evrim Suna Arıkan, Şükrü Ateş, Seher Yılmaz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Osman ÖztürkYozgat Bozok University, Faculty of Medicine, Department of Pediatric Health and Diseases, Yozgat, Turkey.
Sümeyye UçarErciyes University, Faculty of Medicine, Department of Anatomy, Kayseri, Turkey.
Züleyha DoğanyiğitYozgat Bozok University, Faculty of Medicine, Department of Histology and Embryology, Yozgat, Turkey.
Aslı Okan OflamazYozgat Bozok University, Faculty of Medicine, Department of Histology and Embryology, Yozgat, Turkey.
Evrim Suna ArıkanAfyonkarahisar Health Sciences University, Faculty of Medicine, Department of Medical Biology, Afyonkarahisar, Turkey.
Şükrü AteşYozgat Bozok University, Faculty of Medicine, Department of Anatomy, Yozgat, Turkey.
Seher YılmazYozgat Bozok University, Faculty of Medicine, Department of Anatomy, Yozgat, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tartrazine finds widespread application in the realms of alimentation, pharmaceuticals, cosmetic formulations, and textile manufacturing. Tartrazine has a negative effect on human health such as hyperactivity, allergies and asthma in children. Substances such as tartrazine might effect the embryo in a kind of aspects, containing physical or mental disorders, and a decrease in the child's intellectual memory. In this study, Sprague dawley female rats, 70-100 days old, weighing 250-300 g, with confirmed pregnancy, were divided into two groups of 5: control and tartrazine group. Rats were sacrificed on the 20th day and heart, lung, kidney and liver tissues were removed from the fetuses. The effect of tartrazine on fetal bone development was assessed by double skeletal staining, histological analysis on organs, and

Indexed as

Double skeleton stainingFood dyeRat fetusesTartrazineTeratogenic effect

Identifiers

PMID39866447
PMCPMC11758127

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.