Evidence map›Paper›PMID 39866331›Full record

ArticlePsychiatric annals2022

Transcranial Alternating Current Stimulation (tACS) for Major Depressive Disorder.

Julie A Clancy, Justin Riddle, Paolo Cassano, Flavio Frohlich

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychiatric annals, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julie A ClancyHarvard Medical School, Department of Psychiatry, Boston, Massachusetts (JAC, PC); Division of Neuropsychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (JAC, PC); Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (JR, FF); Carolina Center for Neurostimulation, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (JR, FF); Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (PC); Center for Anxiety and Traumatic Stress Disorders, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (PC); Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); and Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF).
Justin RiddleHarvard Medical School, Department of Psychiatry, Boston, Massachusetts (JAC, PC); Division of Neuropsychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (JAC, PC); Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (JR, FF); Carolina Center for Neurostimulation, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (JR, FF); Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (PC); Center for Anxiety and Traumatic Stress Disorders, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (PC); Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); and Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF).
Paolo CassanoHarvard Medical School, Department of Psychiatry, Boston, Massachusetts (JAC, PC); Division of Neuropsychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (JAC, PC); Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (JR, FF); Carolina Center for Neurostimulation, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (JR, FF); Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (PC); Center for Anxiety and Traumatic Stress Disorders, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (PC); Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); and Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF).
Flavio FrohlichHarvard Medical School, Department of Psychiatry, Boston, Massachusetts (JAC, PC); Division of Neuropsychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (JAC, PC); Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (JR, FF); Carolina Center for Neurostimulation, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (JR, FF); Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (PC); Center for Anxiety and Traumatic Stress Disorders, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts (PC); Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF); and Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (FF).

Funding

Causal role of delta-beta coupling for goal-directed behavior in anhedoniaK99MH126161 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RIDDLE, JUSTIN M · 2021 to 2022
$184k
NIMH NIH HHS K99 MH126161
6 · The paper itself

Abstract

The 21st century has brought forth major advancements in device-based treatments for psychiatric disorders such as major depressive disorder (MDD). One of the most exciting technologies on the rise in this field is transcranial alternating current stimulation (tACS). The small but rapidly growing body of knowledge on tACS suggests that this wearable, low-cost, noninvasive neuromodulation method could provide a safe and effective alternative, or augmentation, to pharmacological interventions for MDD. While device parameters for treatment of MDD need refinement before this method is ready for standardized clinical use, we expect that tACS will make a significant impact on psychiatric treatment in the coming years.

Identifiers

PMID39866331
PMCPMC11759093

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.