Evidence map›Paper›PMID 39866244›Full record

ArticleHealth services & outcomes research methodology2023

Evaluating Federal Policies Using Bayesian Time Series Models: Estimating the Causal Impact of the Hospital Readmissions Reduction Program.

Georgia Papadogeorgou, Fiammetta Menchetti, Christine Choirat, Jason H Wasfy, Corwin M Zigler, Fabrizia Mealli

Abstract read
In one paragraph

Article in Health services & outcomes research methodology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Georgia PapadogeorgouUniversity of Florida, Department of Statistics, Gainesville, FL, USA.ORCID 0000-0002-1982-2245
Fiammetta MenchettiUniversity of Florence, DiSIA and Florence Center for Data Science, Florence, Italy.ORCID 0000-0003-3463-0206
Christine ChoiratSwiss Data Science Center, ETH Zürich and EPFL, Lausanne & Institute of Global Health, Faculty of medicine, University of Geneva, Switzerland.
Jason H WasfyCardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Corwin M ZiglerUniversity of Texas at Austin, Department of Statistics and Data Science, Department of Women's Health, Austin, TX, USA.
Fabrizia MealliUniversity of Florence, DiSIA and Florence Center for Data Science, and European University Institute, Department of Economics, Florence, Italy.ORCID 0000-0002-1076-9249

Funding

Harvard Clinical and Translational Science CenterKL2TR001100 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$8.5M
Project 3: Cumulative Risk and Geospatial Health Disparities Related to Chemical and Non-Chemical Stressor ExposuresP50MD010428 · NIMHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI LADEN, FRANCINE · 2015 to 2020
$4.0M
Relationship Between Multiple Environmental Exposures and CVD Incidence and Survival: Vulnerability and SusceptibilityR01ES028033 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI DOMINICI, FRANCESCA, LADEN, FRANCINE · 2018 to 2022
$3.5M
Machine Learning for Health Outcomes and Quality of Care in Low-Income PopulationsDP2MD012722 · NIMHD · STANFORD UNIVERSITY · PI ROSE, SHERRI · 2017 to 2017
$2.5M
Cardiovascular Health and Air Pollution: A National StudyR01ES024332 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI ZANOBETTI, ANTONELLA · 2015 to 2018
$2.5M
Bayesian Methods for Comparative Effectiveness Research with Observational DataR01GM111339 · NIGMS · HARVARD MEDICAL SCHOOL · PI NORMAND, SHARON-LISE TERESA · 2015 to 2018
$2.5M
Causal Inference with Interference for Evaluating Air Quality PoliciesR01ES026217 · NIEHS · UNIVERSITY OF TEXAS AT AUSTIN · PI ZIGLER, CORWIN MATTHEW · 2016 to 2021
$2.2M
American Heart Association-American Stroke Association 18CDA34110215NCATS NIH HHS KL2 TR001100NIEHS NIH HHS R01 ES024332NIEHS NIH HHS R01 ES026217NIEHS NIH HHS R01 ES028033NIGMS NIH HHS R01 GM111339NIMHD NIH HHS DP2 MD012722NIMHD NIH HHS P50 MD010428
6 · The paper itself

Abstract

Researchers are often faced with evaluating the effect of a policy or program that was simultaneously initiated across an entire population of units at a single point in time, and its effects over the targeted population can manifest at any time period afterwards. In the presence of data measured over time, Bayesian time series models have been used to impute what would have happened after the policy was initiated, had the policy not taken place, in order to estimate causal effects. However, the considerations regarding the definition of the target estimands, the underlying assumptions, the plausibility of such assumptions, and the choice of an appropriate model have not been thoroughly investigated. In this paper, we establish useful estimands for the evaluation of large-scale policies. We discuss that imputation of missing potential outcomes relies on an assumption which, even though untestable, can be partially evaluated using observed data. We illustrate an approach to evaluate this key causal assumption and facilitate model elicitation based on data from the time interval before policy initiation and using classic statistical techniques. As an illustration, we study the Hospital Readmissions Reduction Program (HRRP), a US federal intervention aiming to improve health outcomes for patients with pneumonia, acute myocardial infraction, or congestive failure admitted to a hospital. We evaluate the effect of the HRRP on population mortality among the elderly across the US and in four geographic subregions, and at different time windows. We find that the HRRP increased mortality from pneumonia and acute myocardial infraction across at least one geographical region and time horizon, and is likely to have had a detrimental effect on public health.

Indexed as

Bayesian methodscausal inferencehospital readmissions reduction programmortalitypolicy evaluationtime-series

Identifiers

PMID39866244
PMCPMC11758246

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.