ArticleTherapeutic advances in respiratory disease
Association between albumin corrected anion gap and in-hospital mortality in critically ill patients with chronic obstructive pulmonary disease.
Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Association between albumin-corrected anion gap and in-hospital mortality in ICU patients with lung cancer: a retrospective cohort study based on the MIMIC database.Journal of thoracic disease · 2026Article
- Association of ACAG with short-term mortality in liver failure patients: a retrospective analysis based on the MIMIC-IV database.Scientific reports · 2026Article
- Article
- Albumin-corrected anion gap and risk of mortality among US adults.Archives of public health = Archives belges de sante publique · 2025Article
- Prognostic value of albumin-corrected anion gap in severe chronic kidney disease with sepsis: association with mortality and clinical outcomes.European journal of medical research · 2025Article
- Association of albumin-corrected anion gap with mortality in ICU patients with heart failure and acute kidney injury: analysis of the MIMIC-IV database.European journal of medical research · 2025Article
- Prognostic value of albumin-corrected anion gap in critically ill patients with sepsis-associated liver injury: a retrospective study.BMC infectious diseases · 2025Article
- Albumin-corrected anion gap predicts acute kidney injury in critically ill patients with acute pancreatitis: a retrospective cohort study.BMC nephrology · 2025Article
- Article
- Association between changes in corrected anion gap and mortality among critically ill patients during ICU stay: a multicenter observational study.Frontiers in physiology · 2025Article
- Relationship between albumin-corrected anion gap and short- and medium-term all-cause mortality in heart failure patients with a single ICU admission.Frontiers in cardiovascular medicine · 2025Article
- Association between anion gap and postoperative delirium in patients undergoing open heart surgery.Frontiers in cardiovascular medicine · 2025Article
- The Association Between Anion Gap and Albumin-Corrected Anion Gap with Sun Sensitivity: A National Retrospective Cross-Sectional Study.Clinical, cosmetic and investigational dermatology · 2025Article
- Prognostic Value of the Albumin Corrected Anion Gap in ICU Patients with Chronic Obstructive Pulmonary Disease and Sepsis: A MIMIC-IV Cohort Study.International journal of chronic obstructive pulmonary disease · 2025Article
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4 authors.
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Abstract
backgroundThe relationship between albumin-corrected anion gap (ACAG) and in-hospital mortality in critically ill patients with COPD remains unclear.
objectiveThis study investigated the association between ACAG levels and the risk of in-hospital mortality in critically ill patients with COPD.
designA retrospective cohort study.
methodsThis study uses data from the Medical Information Mart for Intensive Care (MIMIC-IV) database. The receiver operating characteristic (ROC) curve was used to determine the optimal threshold for ACAG, and participants were divided into two categories based on this threshold. The primary outcome was in-hospital mortality. We employed univariable and multivariable logistic regression analyses and Kaplan-Meier (KM) survival curves to assess the relationship between ACAG and the risk of in-hospital mortality. Moreover, subgroup analyses were conducted.
resultsA total of 2121 patients (54.7% male) were enrolled in the study. The in-hospital mortality rate was 18.9%. In patients with elevated ACAG levels, the in-hospital mortality rate was significantly higher than in those with lower ACAG levels (27.7% vs 11.3%,
conclusionThis study demonstrates that elevated ACAG levels are strongly associated with an increased risk of in-hospital mortality in critically ill COPD patients, suggesting that ACAG could serve as a potential predictor of adverse outcomes in this patient population.
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