ArticleJournal of Alzheimer's disease : JAD2025
Gait, balance, and physical performance as markers of early Alzheimer's disease and related dementia risk.
Article in Journal of Alzheimer's disease : JAD, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Dual-task versus single-task walking within an Otago Exercise Program for older adults with dementia: A 24-week cluster randomized controlled trial.Journal of exercise science and fitness · 2026Article
- Wearable sensing for quantifying cognitive and balance functions in naturalistic movements of older adults with mild cognitive impairment in therapeutic environments.medRxiv : the preprint server for health sciences · 2026Article
- [Progress on prognostic assessment methods for mild cognitive impairment].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026Review
- Assessment of Bidirectional and Threshold-Response Associations Between Cognitive Function and Physical Performance: Nationwide Cross-Sectional Study.JMIR public health and surveillance · 2025Article
- Machine learning-based estimation of the mild cognitive impairment stage using multimodal physical and behavioral measures.Scientific reports · 2025Article
- Using AI-Based Gait Analysis to Establish a 5-Meter Walk Time Cutoff for Discriminating Alzheimer's Disease.Cureus · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
BackgroundDeclining physical functionality is an indicator of cognitive impairment, distinguishing normal cognition (NC) from dementia. Whether this extends to pre-dementia stages is unclear.ObjectiveAssess physical performance patterns, evaluate relationships with imaging biomarkers, and identify specific measures distinguishing NC, subjective cognitive decline (SCD) and mild cognitive impairment (MCI).MethodsGroup differences (78 NC, 35 SCD, and 41 MCI) in physical function (global function, balance, gait speed, step length, single leg support) were evaluated with logistic regression while distinguishing between MCI due-to-AD and MCI due-to-vascular etiology. Relationships with imaging biomarkers (cortical atrophy score, white matter hyperintensities volumes) were analyzed with ANCOVA.ResultsParticipants were 68.6 ± 9.3 years old, had 16.2 ± 3.0 years of education, and 23% were ethnoracial minorities. Physical performance distinguished MCI from NC and SCD. Greater performance on the Mini Physical Performance Test (mini PPT) and balance were associated with lower odds of being SCD versus NC (OR
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