ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2025
Longitudinal measures of peripheral optical quality in young children.
Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Longitudinal changes in retinal image quality in school-aged children.Biomedical optics express · 2026Article
- Effect of Binocularity and Depth on Static and Dynamic Accommodation Responses in Young Children.Investigative ophthalmology & visual science · 2026Article
- Asymmetry between nasal and temporal refraction with accommodation in myopes and emmetropes.Biomedical optics express · 2026Article
- Longitudinal Evaluation of Static and Dynamic Accommodation in Young Children.Investigative ophthalmology & visual science · 2025Article
- Relative peripheral refraction with accommodation in 6- to 11-year-olds: baseline findings from the Stockholm Myopia Study.Biomedical optics express · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeTo assess longitudinal changes in optical quality across the periphery (horizontal meridian, 60°) in young children who are at high (HR) or low risk (LR) of developing myopia, as well as a small subgroup of children who developed myopia over a 3-year time frame.
methodsAberrations were measured every 6 months in 92 children with functional emmetropia at baseline. Children were classified into HR or LR based on baseline refractive error and parental myopia. Zernike polynomials were calculated for 4 mm pupils, accounting for the elliptical shape of the pupil in the periphery. Various metrics were computed, including Strehl Ratios with only high-order aberrations (HO-SR). Primary spherical aberration (SA), horizontal coma and defocus were also analysed given their relevance in emmetropisation. The areas under the image quality metrics for various regions of interest were computed.
resultsHO-SR were higher in children at HR and children with myopia, even when SA was removed from the Strehl Ratio (SR) calculation. SA was less positive in children at HR and children with myopia. Defocus was more negative in children at HR and children with myopia at all eccentricities and was even more negative when computed relative to the fovea, an effect that increased in the mid periphery. Relative peripheral defocus also became more negative over time in children at HR and children with myopia at the mid temporal retina. The other aberrations showed no significant changes in time overall.
conclusionsThis longitudinal study showed differences in HO-SR, SA and defocus in the central and near-peripheral retina (±20°) of young children at HR before they develop myopia compared with children at LR for myopia. The results may indicate these eccentricities are significant in providing signals for emmetropisation. The small changes noted over time may indicate that the differences are a cause of myopia development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.