Evidence map›Paper›PMID 39865273›Full record

ArticleWorld journal of emergency surgery : WJES2025

Feasibility and accuracy of continuous intraabdominal pressure monitoring with a capsular device in human pilot trial.

Chien-Hung Liao, David A Spain, Chih-Chi Chen, Chi-Tung Cheng, Wei-Cheng Lin, Dong-Ru Ho, Heng-Fu Lin, Fausto Catena

Abstract read
In one paragraph

Article in World journal of emergency surgery : WJES, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chien-Hung Liao *Department of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.
David A Spain *Department of Surgery, Stanford University, Stanford, CA, USA.
Chih-Chi ChenDepartment of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.
Chi-Tung ChengDepartment of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.
Wei-Cheng LinDepartment of Electrical Engineering, Chang Gung University, Taoyuan, Taiwan.
Dong-Ru HoDepartment of Surgery, Division of Urology, Chang Gung Memorial Hospital, Chang Gung University, Puzi City, Chiayi, Taiwan. redoxdrh@gmail.com.
Heng-Fu LinDivision of Trauma, Department of Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Fausto CatenaUniversity of Bologna- Bufalini Hospital, Cesena, Italy.

Funding

Chang Gung Medical Foundation CORPG6M0181National Science and Technology Council NMRPG6P0101National Science and Technology Council NSTC 113-2314-B-182A-070 -MY3
6 · The paper itself

Abstract

backgroundIntrabdominal pressure (IAP) is an important parameter. Elevated IAP can reduce visceral perfusion, lead to intraabdominal hypertension, and result in life-threatening abdominal compartment syndrome. While ingestible capsular devices have been used for various abdominal diagnoses, their application in continuous IAP monitoring remains unproven.

methodWe conducted a prospective clinical trial to evaluate the feasibility of IAP measurement using a digital capsule PressureDOT, an ingestible capsule equipped with wireless transmission capability and a pressure sensor, then compared its reliability with conventional intravesical method. Patients undergoing laparoscopic or robotic surgeries were recruited. During surgery, we created pneumoperitoneum by inflating CO2 into the peritoneal cavity and IAP was simultaneously monitored using both the ingestible capsules and intravesical measurements from Foley catheter. We assessed the feasibility of signal transmission and the accuracy of pressure measurements.

resultsSix patients were enrolled in this pilot study. No adverse events were reported, and the average first-intake time was within 24 h. All capsules were successfully expelled, with an average excretion time of 81 h. In the summarized data, the mean IAPdot is 0.6 mmHg lower than the IAPivp, with a standard deviation of 1.68 mmHg. However, capsule measurements showed excellent correlation with intravesical IAP measurements, with an intraclass correlation coefficient of 0.916 (95% CI: 0.8821-0.9320).

conclusionOur study demonstrates the feasibility and safety of using digital capsules for continuous IAP monitoring, providing the agreement between IAP measurements from digital capsules and conventional intravesical measurement within a near-normal pressure.

Indexed as

Intra-Abdominal HypertensionAbdominal CavityAdultAgedFeasibility StudiesFemaleHumansMaleMiddle AgedMonitoring, PhysiologicPilot ProjectsPressureProspective StudiesReproducibility of ResultsAbdominal compartment syndromeCapsular sensorDigital healthIntraabdominal pressure

Identifiers

PMID39865273
PMCPMC11771060

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.