Effect of external infusion connection devices replacement frequency on catheter related bloodstream infection.

Wenchao Wang, Yuqing Wang, Yulu Xu, Weijie Shen, Guoping Lu, Ying Gu

Abstract readObservational Study

In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenchao WangPediatric Intensive Care Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.

Yuqing WangPediatric Intensive Care Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.

Yulu XuCardiac Intensive Care Unit, Children's Hospital of Fudan University,National Children's Medical Center, Shanghai, China.

Weijie ShenPediatric Intensive Care Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.

Guoping LuPediatric Intensive Care Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.

Ying GuNursing Department, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China. guying_gy@fudan.edu.cn.

Funding

Fudan University FNDGJ202008Shanghai Shen Kang Hospital Development Center SHDC22023240

6 · The paper itself

Abstract

Timely and effective rescue of critically ill children no longer solely relies on advanced medical technology; vascular access plays a pivotal role. Best practice recommendations for nursing in vascular access are critical for ICU patients. However, clear guidelines for the maintenance of external infusion connection devices remain lacking. To address this gap, we conducted a prospective observational cohort study to examine the relationship between the number or replacement frequency of external infusion connection devices and catheter-related bloodstream infection (CRBSI). From September 2021 to December 2022, a total of 304 patients with a single non-tunneled central catheter were enrolled in our study. Our findings revealed no significant differences in CRBSI incidence based on the number or replacement frequency of external infusion connection devices during the catheter's indwelling time (P > 0.05). Notably, coagulase-negative staphylococci, particularly Staphylococcus epidermidis, were the predominant pathogens in CRBSI cases.In real-world clinical settings, adherence to strict aseptic principles during infusion set use and replacement appeared to mitigate the correlation between device replacement frequency or number and CRBSI incidence.

Indexed as

BacteremiaCatheterization, Central VenousCatheter-Related InfectionsCatheters, IndwellingCentral Venous CathetersAdultAgedChildFemaleHumansIncidenceIntensive Care UnitsMaleMiddle AgedProspective StudiesStaphylococcus epidermidisCatheter related bloodstream infectionCentral venous catheterInfusion setPediatrics

Identifiers

PMID39865114

DOI10.1038/s41598-025-87310-2

PMCPMC11770091

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.