Evidence map›Paper›PMID 39864505›Full record

ArticleChest2025

Use of High-Dose Hydroxocobalamin for Septic Shock.

Jason R Carr, Brian Locke, Jayshil J Patel, Ithan D Peltan, Samuel M Brown, Nicholas A Bosch, Anica C Law

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chest, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jason R CarrDepartment of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, UT; Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, UT. Electronic address: Jason.Carr@imail.org.
Brian LockeDepartment of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, UT; Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, UT.
Jayshil J PatelDivision of Pulmonary and Critical Care Medicine, Medical College of Wisconsin, Milwaukee, WI.
Ithan D PeltanDepartment of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, UT; Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, UT.
Samuel M BrownDepartment of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, UT; Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, UT.
Nicholas A BoschDepartment of Medicine, The Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Anica C LawDepartment of Medicine, The Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.

Funding

Measuring and Learning from Care Variation in SepsisR35GM151147 · NIGMS · IHC HEALTH SERVICES, INC. · PI Ithan Daniel Peltan · 2023 to 2026
$1.5M
Prolonged mechanical ventilation: patterns of post-acute care and patient outcomesK23HL153482 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAW, ANICA C · 2020 to 2024
$891k
NHLBI NIH HHS K23 HL153482NIGMS NIH HHS R35 GM151147
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39864505
PMCPMC12264341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.