Evidence map›Paper›PMID 39864448›Full record

ArticleThe Lancet. Infectious diseases2025

Antiviral activity of tecovirimat against monkeypox virus clades 1a, 1b, 2a, and 2b.

Jeanne Postal, Florence Guivel-Benhassine, Françoise Porrot, Quentin Grassin, Jack M Crook, Riccardo Vernuccio, Valérie Caro, Jessica Vanhomwegen, Pablo Guardado-Calvo, Etienne Simon-Lorière and 3 more

Abstract readLetter
In one paragraph

Article in The Lancet. Infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. A 2-week old infant with Mpox in Uganda: a case report.Journal of medical case reports · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jeanne PostalVirus and Immunity Unit, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France; Vaccine Research Institute, Paris, France.
Florence Guivel-BenhassineVirus and Immunity Unit, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France; Vaccine Research Institute, Paris, France.
Françoise PorrotVirus and Immunity Unit, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France; Vaccine Research Institute, Paris, France.
Quentin GrassinLaboratory for Urgent Response to Biological Threats, Environment and Infectious Risks, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France.
Jack M CrookEvolutionary Genomics of RNA Viruses, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France.
Riccardo VernuccioStructural Biology of Infectious Diseases, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France.
Valérie CaroLaboratory for Urgent Response to Biological Threats, Environment and Infectious Risks, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France.
Jessica VanhomwegenLaboratory for Urgent Response to Biological Threats, Environment and Infectious Risks, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France.
Pablo Guardado-CalvoStructural Biology of Infectious Diseases, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France.
Etienne Simon-LorièreEvolutionary Genomics of RNA Viruses, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France.
Laurent DacheuxLaboratory for Urgent Response to Biological Threats, Environment and Infectious Risks, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France.
Jean-Claude ManuguerraLaboratory for Urgent Response to Biological Threats, Environment and Infectious Risks, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France.
Olivier SchwartzVirus and Immunity Unit, Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique UMR3569, Paris 75015, France; Vaccine Research Institute, Paris, France. Electronic address: olivier.schwartz@pasteur.fr.

Funding

Inter-regional study of transmission, adaptation and pathogenesis of viruses with pandemic potential in Southeast Asia and West/Central AfricaU01AI151758 · NIAID · INSTITUT PASTEUR · PI SAKUNTABHAI, ANAVAJ, SIMON-LORIERE, ETIENNE · 2020 to 2024
$6.7M
NIAID NIH HHS U01 AI151758
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39864448
PMCPMC12579807

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.