Evidence map›Paper›PMID 39863962›Full record

Observational studyActa dermato-venereologica2025

Epidemiology and Management of Actinic Keratosis in France: A General Population Survey (REAKT).

Brigitte Dréno, Pierre Lévy, Gregory Caillet, Chantal Touboul, Jean-Michel Joubert, Jean-Michel Amici

Abstract readObservational Study
In one paragraph

Observational study in Acta dermato-venereologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brigitte DrénoNantes University, INSERM, CNRS, Immunology and New Concepts in Immunotherapy, UMR 1302/EMR6001, Nantes, France. brigitte.dreno@atlanmed.fr.ORCID 0000-0001-5574-5825
Pierre LévyParis-Dauphine University, PSL University, LEDA[LEGOS], Paris, France.ORCID 0000-0001-7565-2255
Gregory CailletMedical Affairs Department, Almirall SAS, Paris, France.
Chantal TouboulCerner Enviza France, Paris, France.ORCID 0000-0002-7843-5464
Jean-Michel JoubertGovernment Affairs Department, Almirall SAS, Paris, France.
Jean-Michel AmiciDepartment of Dermatology, Saint-André Hospital, Bordeaux University Hospital, Bordeaux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this retrospective observational study was to estimate the prevalence of actinic keratosis (AK) in individuals aged ≥ 40 years in France, to describe the characteristics of affected patients, and to describe treatments. A representative panel of 20,000 households with ≥ 1 member aged ≥ 40 years were invited to participate. Participants who reported AK lesions diagnosed by a physician were eligible. The study questionnaire collected data on demographics, lesion characteristics, Fitzpatrick phototype, diagnosis, and treatments. In total, 15,246 questionnaires (78.5%) were returned and 639 responders were eligible. The adjusted prevalence of AK was 4.03% (95% CI: 3.73-4.35). Prevalence is probably underestimated due to data collection by self-report and low awareness of AK. 177 participants (27.7%) were aged < 65 years. AK was diagnosed by a dermatologist for 521 participants (81.6%). Some 200 participants (31.3%) had no lesions at the time of the survey and 243 (37.9%) had never been treated; 312 participants (78.6%) were prescribed physical treatment, principally cryotherapy; and 125 (31.5%) were prescribed topical treatment, principally 5-fluorouracil or imiquimod. In conclusion, improving diagnosis of AK in everyday clinical practice is important to ensure that all individuals with AK are treated optimally and encouraged to take sun protection measures to prevent progression to SCC.

Indexed as

Keratosis, ActinicAdultAgedAged, 80 and overCryotherapyFemaleFluorouracilFranceHealth SurveysHumansMaleMiddle AgedPrevalenceRetrospective StudiesSunlightTreatment OutcomeFluorouracil

Identifiers

PMID39863962
PMCPMC11788678

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.