Evidence map›Paper›PMID 39863620›Full record

ArticleScientific reports2025

Atmospheric air plasma pre-activation and customizable covalent functionalization of PVDF-membranes of microtiter filter plates.

Bálint Árpád Ádám, Sára Spátay, Bálint Jávor, Szabolcs László, Levente Illés, Péter Fürjes, Tünde Tóth, Péter Huszthy, Ádám Golcs

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Bálint Árpád ÁdámDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Szent Gellért Tér 4, 1111, Budapest, Hungary.
Sára SpátayDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Szent Gellért Tér 4, 1111, Budapest, Hungary.
Bálint JávorDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Szent Gellért Tér 4, 1111, Budapest, Hungary.
Szabolcs LászlóDepartment of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Szent Gellért Tér 4, 1111, Budapest, Hungary.
Levente IllésInstitute of Technical Physics and Materials Science, HUN-REN Centre for Energy Research, Konkoly-Thege Miklós U. 29-33, 1121, Budapest, Hungary.
Péter FürjesInstitute of Technical Physics and Materials Science, HUN-REN Centre for Energy Research, Konkoly-Thege Miklós U. 29-33, 1121, Budapest, Hungary.
Tünde TóthDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Szent Gellért Tér 4, 1111, Budapest, Hungary.
Péter HuszthyDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, Szent Gellért Tér 4, 1111, Budapest, Hungary.
Ádám GolcsDepartment of Pharmaceutical Chemistry, Semmelweis University, Hőgyes Endre U. 9, 1092, Budapest, Hungary. golcs.adam@semmelweis.hu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microtiter-plate-based systems are unified platforms of high-throughput experimentation (HTE). These polymeric devices are used worldwide on a daily basis-mainly in the pharmaceutical industry-for parallel syntheses, reaction optimization, various preclinical studies and high-throughput screening methods. Accordingly, laboratory automation today aims to handle these commercially available multiwell plates, making developments focused on their modifications a priority area of modern applied research. We performed the covalent functionalization of the porous PVDF-membrane of microtiter filter plates as the essence of conventional and common sandwich plate systems by introducing a generalizable method. After surface-activation of the indifferent membrane polymer, customizable functionalization becomes feasible by covalently attached monofunctional molecular linkers. The study was designed with future adaptability, and thus, industrially widespread atmospheric plasma and two different chemical treatments were investigated and compared in terms of practical implementation, polarization effects, extent of labeling, effects on morphology and porosity as well as on permeability. For critical comparison, contact angle measurements, surface ATR-FTIR,

Indexed as

Covalent immobilizationMembranePlasmaPVDFSurface polarization

Identifiers

PMID39863620
PMCPMC11762284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.