Evidence map›Paper›PMID 39862246›Full record

ArticlePflugers Archiv : European journal of physiology2025

Spatio-temporal segregation between sensory relay and swallowing pre-motor population activities by optical imaging in the rat nucleus of the solitary tract.

Shinya Fuse, Yoichiro Sugiyama, Rishi R Dhingra, Shigeru Hirano, Mathias Dutschmann, Yasumasa Okada, Yoshitaka Oku

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Research advances in dysphagia animal models.Animal models and experimental medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shinya FuseDepartment of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kyoto, 602-8566, Japan. fuse@koto.kpu-m.ac.jp.
Yoichiro SugiyamaDepartment of Otolaryngology-Head and Neck Surgery, Saga University Faculty of Medicine, Saga, 849-8501, Japan.
Rishi R DhingraDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine Case Western Reserve University, Cleveland, OH, 44106, USA.
Shigeru HiranoDepartment of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kyoto, 602-8566, Japan.
Mathias DutschmannDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine Case Western Reserve University, Cleveland, OH, 44106, USA.
Yasumasa OkadaClinical Research Center, Murayama Medical Center, Musashimurayama, Tokyo, 208-0011, Japan.
Yoshitaka OkuDivision of Neurophysiology, Department of Physiology, Hyogo Medical University, Hyogo, 663 8501, Japan.

Funding

Japan Society for Promotion of Science 22K09671
6 · The paper itself

Abstract

The nucleus tractus solitarius (NTS) contains neurons that relay sensory swallowing commands information from the oropharyngeal cavity and swallowing premotor neurons of the dorsal swallowing group (DSG). However, the spatio-temporal dynamics of the interplay between the sensory relay and the DSG is not well understood. Here, we employed fluorescence imaging after microinjection of the calcium indicator into the NTS in an arterially perfused brainstem preparation of rat (n = 8) to investigate neuronal population activity in the NTS in response to superior laryngeal nerve (SLN) stimulation. Respiratory and swallowing motor activities were determined by simultaneous recordings of phrenic and vagal nerve activity (PNA, VNA). The analysis of SLN stimulation near the threshold triggering a swallowing allowed us to analyze Ca

Indexed as

DeglutitionSensory Receptor CellsSolitary NucleusAnimalsLaryngeal NervesMaleMotor NeuronsOptical ImagingRatsRats, Sprague-DawleyRats, WistarVagus NerveCalcium imagingDorsal swallowing groupIn situ perfused brainstem preparationOptical recordingSLN-evoked swallowing

Identifiers

PMID39862246
PMCPMC12003619

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.