Evidence map›Paper›PMID 39862188›Full record

ArticleJournal of the American Chemical Society2025

EPR Characterization of the BlsE Substrate Radical Offers Insight into the Determinants of Reaction Outcome that Distinguish Radical SAM Dioldehydratases from Dehydrogenases.

Baixu Ma, Yu-Hsuan Lee, Mark W Ruszczycky, Daan Ren, Amelia Engstrom, Hung-Wen Liu, Lizhi Tao

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Baixu MaDepartment of Chemistry, Southern University of Science and Technology, Shenzhen 518055, China.
Yu-Hsuan LeeDivision of Chemical Biology & Medicinal Chemistry, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, United States.
Mark W RuszczyckyDivision of Chemical Biology & Medicinal Chemistry, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, United States.
Daan RenDivision of Chemical Biology & Medicinal Chemistry, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0002-1309-5382
Amelia EngstromDivision of Chemical Biology & Medicinal Chemistry, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, United States.
Hung-Wen LiuDivision of Chemical Biology & Medicinal Chemistry, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0001-8953-4794
Lizhi TaoDepartment of Chemistry, Southern University of Science and Technology, Shenzhen 518055, China.ORCID 0000-0001-9921-2297

Funding

Mechanistic Studies of Deoxy Sugar BiosynthesisR01GM035906 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI LIU, HUNG-WEN · 1986 to 2023
$6.1M
MECHANISMS OF BIOSYNTHETIC FORMATION OF DEOXY SUGARSR37GM035906 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI LIU, HUNG-WEN · 1999 to 2008
$3.4M
Novel Mechanisms of Catalysis in Natural Product BiosynthesisR35GM153203 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI HUNG-WEN LIU · 2024 to 2026
$2.0M
NIGMS NIH HHS R01 GM035906NIGMS NIH HHS R35 GM153203NIGMS NIH HHS R37 GM035906
6 · The paper itself

Abstract

A small but growing set of radical SAM (

Indexed as

OxidoreductasesS-AdenosylmethionineElectron Spin Resonance SpectroscopyFree RadicalsSubstrate SpecificityFree RadicalsOxidoreductasesS-Adenosylmethionine

Identifiers

PMID39862188
PMCPMC11826333

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.