Evidence map›Paper›PMID 39861877›Full record

ArticleViruses2025

The Dissemination of Rift Valley Fever Virus to the Eye and Sensory Neurons of Zebrafish Larvae Is Stat1-Dependent.

Sebastiaan Ter Horst, Aleksandra Siekierska, Ann-Sofie De Meulemeester, Arno Cuvry, Laura Cools, Johan Neyts, Peter de Witte, Joana Rocha-Pereira

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sebastiaan Ter HorstDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0001-7981-6376
Aleksandra SiekierskaDepartment of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0003-4907-605X
Ann-Sofie De MeulemeesterDepartment of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
Arno CuvryDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0002-8360-9510
Laura CoolsDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
Johan NeytsDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0002-0033-7514
Peter de WitteDepartment of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0002-9989-9567
Joana Rocha-PereiraDepartment of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0001-8299-3787

Funding

KU Leuven C24/18/080Research Foundation - Flanders 11F2919N
6 · The paper itself

Abstract

The Rift Valley fever virus (RVFV) causes haemorrhagic fever, encephalitis, and permanent blindness and has been listed by the WHO as a priority pathogen. To study RVFV pathogenesis and identify small-molecule antivirals, we established a novel In Vivo model using zebrafish larvae. Pericardial injection of RVFV resulted in ~4 log

Indexed as

EyeRift Valley FeverRift Valley fever virusSensory Receptor CellsSTAT1 Transcription FactorZebrafishAnimalsDisease Models, AnimalLarvaPyrazolesVirus ReplicationPyrazolesSTAT1 Transcription Factorbunyavirusinnate immunitypathogenesisrift valley fever viruszebrafish

Identifiers

PMID39861877
PMCPMC11768566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.