Evidence map›Paper›PMID 39861818›Full record

ReviewViruses2024

Assessing the Burden of Neglected Tropical Diseases in Low-Income Communities: Challenges and Solutions.

Francesco Branda, Abdisalam Yusuf Ali, Giancarlo Ceccarelli, Mattia Albanese, Erica Binetti, Marta Giovanetti, Massimo Ciccozzi, Fabio Scarpa

Abstract readReview
In one paragraph

Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Insecticidal Potential ofPlants (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francesco BrandaUnit of Medical Statistics and Molecular Epidemiology, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0002-9485-3877
Abdisalam Yusuf AliSchool of Public Health, Mount Kenya University, Thika P.O. Box 342-01000, Kenya.ORCID 0009-0002-0888-1386
Giancarlo CeccarelliDepartment of Public Health and Infectious Diseases, University of Rome Sapienza, 00161 Rome, Italy.ORCID 0000-0001-5921-3180
Mattia AlbaneseDepartment of Public Health and Infectious Diseases, University of Rome Sapienza, 00161 Rome, Italy.
Erica BinettiDepartment of Public Health and Infectious Diseases, University of Rome Sapienza, 00161 Rome, Italy.ORCID 0009-0005-9831-6648
Marta GiovanettiDepartment of Science and Technologies for Sustainable Development and One Health, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0002-5849-7326
Massimo CiccozziUnit of Medical Statistics and Molecular Epidemiology, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0003-3866-9239
Fabio ScarpaDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-3501-714X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neglected tropical diseases (NTDs) represent a group of chronic and debilitating infections that affect more than one billion people, predominantly in low-income communities with limited health infrastructure. This paper analyzes the factors that perpetuate the burden of NTDs, highlighting how poor health infrastructure, unfavorable socioeconomic conditions and lack of therapeutic resources exacerbate their impact. The effectiveness of current interventions, such as mass drug administration (MDA) programs and improved sanitation, in reducing disease prevalence is examined. In addition, the role of climate change, which alters transmission dynamics and expands affected territories, is discussed as an emerging challenge. The analysis suggests that integrated, multisectoral approaches, including health education and infrastructure interventions, are essential to breaking the cycle of poverty and disease. Although international programs have marked significant progress, achieving elimination targets by 2030 requires sustained commitment, innovation, and increased research capacity in endemic countries.

Indexed as

Neglected DiseasesPovertyTropical MedicineClimate ChangeCost of IllnessDeveloping CountriesHumansMass Drug AdministrationPrevalenceand hygiene (WASH)climate changeco-infectioncommunity health educationdisease burdenglobal health initiativeshealth infrastructuremass drug administrationneglected tropical diseasessanitationsocioeconomic impactwater

Identifiers

PMID39861818
PMCPMC11769400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.