Evidence map›Paper›PMID 39861676›Full record

ReviewPharmaceutics2024

A Systematic Review of Spironolactone Nano-Formulations for Topical Treatment of Skin Hyperandrogenic Disorders and Chronic Wounds.

Saedah Dereiah, Muhammad Usman Ghori, Barbara R Conway

Registry-linked trialAbstract readReview
In one paragraph

Review in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07473895 (Efficacy and Safety of Topical 5% Spironolactone Gel Nano-Formulation Versus 0.1% Adapalene Gel in the Management of Acne Vulgaris), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07473895 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Efficacy and Safety of Topical 5% Spironolactone Gel Nano-Formulation Versus 0.1% Adapalene Gel in the Management of Acne Vulgaris: A Split-Face Study

TypeinterventionalSponsorAssiut UniversityRan2026 to 2026Enrolled40ConditionsAcne VulgarisArmsSpironolactone 5% Topical Gel, Adapalene 0.1% Topical Gel
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Saedah DereiahDepartment of Pharmacy, University of Huddersfield, Huddersfield HD1 3DH, UK.
Muhammad Usman GhoriDepartment of Pharmacy, University of Huddersfield, Huddersfield HD1 3DH, UK.ORCID 0000-0003-1884-6648
Barbara R ConwayDepartment of Pharmacy, University of Huddersfield, Huddersfield HD1 3DH, UK.ORCID 0000-0001-5570-3318

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acnedrug permeationnano-formulationsskinspironolactonetransdermal drug deliverywounds

Identifiers

PMID39861676
PMCPMC11768432

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.