Evidence map›Paper›PMID 39861649›Full record

ArticlePlants (Basel, Switzerland)2025

Global Transcriptomic Analysis of Inbred Lines Reveal Candidate Genes for Response to Maize Lethal Necrosis.

Ann Murithi, Gayathri Panangipalli, Zhengyu Wen, Michael S Olsen, Thomas Lübberstedt, Kanwarpal S Dhugga, Mark Jung

Abstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Crop Functional Genomics and Biological Breeding.Plants (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ann MurithiCorteva Agriscience, 7000 NW 62nd Ave, Johnston, IA 50131, USA.
Gayathri PanangipalliCorteva Agriscience, 7000 NW 62nd Ave, Johnston, IA 50131, USA.
Zhengyu WenInternational Maize and Wheat Improvement Center (CIMMYT), Carretera México-Veracruz, Km. 45, Texcoco 56237, Mexico.
Michael S OlsenBayer, Crop Science Division, 800 N. Lindbergh Blvd., St. Louis, MO 63167, USA.ORCID 0000-0002-8818-6238
Thomas LübberstedtDepartment of Agronomy, Iowa State University, 716 Farm House Lane, Ames, IA 50011, USA.ORCID 0000-0002-0526-0798
Kanwarpal S DhuggaInternational Maize and Wheat Improvement Center (CIMMYT), Carretera México-Veracruz, Km. 45, Texcoco 56237, Mexico.
Mark JungCorteva Agriscience, 7000 NW 62nd Ave, Johnston, IA 50131, USA.

Funding

Gates Foundation INV-007833Gates Foundation OPP1193833 and INV-007833
6 · The paper itself

Abstract

Maize lethal necrosis (MLN) is a significant threat to food security in Sub-Saharan Africa (SSA), with limited commercial inbred lines displaying tolerance. This study analyzed the transcriptomes of four commercially used maize inbred lines and a non-adapted inbred line, all with varying response levels to MLN. RNA-Seq revealed differentially expressed genes in response to infection by maize chlorotic mottle virus (MCMV) and sugarcane mosaic virus (SCMV), the causative agents of MLN. Key findings included the identification of components of the plant innate immune system, such as differentially regulated R genes (mainly LRRs), and activation/deactivation of virus resistance pathways, including RNA interference (RNAi) via

Indexed as

disease resistancegene expressionmaizeMCMVMLNRNA-SeqSCMVviruses

Identifiers

PMID39861649
PMCPMC11768128

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.