Evidence map›Paper›PMID 39861559›Full record

ReviewPlants (Basel, Switzerland)2025

Extraction and Processing of Bioactive Phytoconstituents from Widely Used South African Medicinal Plants for the Preparation of Effective Traditional Herbal Medicine Products: A Narrative Review.

Sphamandla Hlatshwayo, Nokukhanya Thembane, Suresh Babu Naidu Krishna, Nceba Gqaleni, Mlungisi Ngcobo

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. A comprehensive review ofBiochemistry and biophysics reports · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sphamandla HlatshwayoTraditional Medicine Laboratory, University of KwaZulu Natal, Durban 4041, South Africa.
Nokukhanya ThembaneTraditional Medicine Laboratory, University of KwaZulu Natal, Durban 4041, South Africa.ORCID 0000-0002-3242-6159
Suresh Babu Naidu KrishnaInstitute for Water and Wastewater Technology, Durban University of Technology, Durban 4000, South Africa.ORCID 0000-0003-3155-8878
Nceba GqaleniTraditional Medicine Laboratory, University of KwaZulu Natal, Durban 4041, South Africa.ORCID 0000-0003-1946-3120
Mlungisi NgcoboTraditional Medicine Laboratory, University of KwaZulu Natal, Durban 4041, South Africa.

Funding

Department of Science and Innovation (DSI), National Research Foundation (NRF), Health and Welfare Sector Education and Training Authority (HWSETA), College of Health Sciences (CHS) and Moses Kotane Institute (MKI) National Research Foundation: PMDS22063029421
6 · The paper itself

Abstract

Medicinal plants are sources of crude traditional herbal medicines that are utilized to reduce the risk of, treat, or manage diseases in most indigenous communities. This is due to their potent antioxidant and anti-inflammatory effects. It is estimated that about 80% of the population in developing countries rely on herbal traditional medicines for healthcare. This signifies the need for traditional herbal medicines, which are polyherbal formulations prepared by traditional health practitioners. This review examines preparatory steps to extract bioactive phytoconstituents and post-extraction processes to increase the potency of the extracted bioactive phytoconstituents. Achieving this will allow for the reduced use of plant materials and promote the sustainable use of the limited resource of medicinal plants, especially in our South African context. Electronic ethnobotanical books and online databases were used to find studies that focus on phytoconstituent extraction and post-extraction processing to enhance the potency of the extracted bioactive phytoconstituents. Modification of the extracted bioactive phytoconstituents to synthesize daughter compounds facilitates an enhancement in their potency and bioavailability. Based on the data collected through this review, the importance of understanding the properties of the targeted phytoconstituents is essential in selecting the required extraction method. This determines the quality and yield of extracted bioactive phytoconstituents.

Indexed as

bioactive phytoconstituentsextractionmedicinal plantspotencyprocessing

Identifiers

PMID39861559
PMCPMC11768456

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.