Evidence map›Paper›PMID 39861486›Full record

ReviewNutrients2025

Dietary Interventions, Supplements, and Plant-Derived Compounds for Adjunct Vitiligo Management: A Review of the Literature.

Michael J Diaz, Jasmine T Tran, Drake Rose, Aria Wei, Deepak Lakshmipathy, Shari R Lipner

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael J DiazCollege of Medicine, University of Florida, Gainesville, FL 32601, USA.
Jasmine T TranSchool of Medicine, Indiana University, Indianapolis, IN 46202, USA.
Drake RoseUniversity of Michigan Medical School, Ann Arbor, MI 48109, USA.
Aria WeiSchool of Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Deepak LakshmipathyCarle Illinois College of Medicine, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-5874-7113
Shari R LipnerDepartment of Dermatology, Weill Cornell Medicine, New York City, NY 10021, USA.ORCID 0000-0001-5913-9304

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitiligo is a chronic autoimmune pigmentation disorder shaped by a complex interplay of genetic predispositions and environmental triggers. While conventional therapies-phototherapy, corticosteroids, and immunosuppressants-can be effective, their benefits are often partial and temporary, with recurrence common once treatment stops. As such, there is increasing interest in exploring complementary approaches that may offer a more sustainable impact. Emerging evidence suggests that macronutrient and micronutrient-level changes could be beneficial for managing progression and, in some cases, facilitating repigmentation. Antioxidant-rich foods, such as apples, green tea, Indian gooseberry, onions, and peppers, may help mitigate oxidative stress, while inflammatory foods, such as gluten and high-phenol nuts and berries, may exacerbate the condition. Certain supplements, including high-dose vitamin D, vitamin C, vitamin E, and selenium, may enhance phototherapy outcomes. Omega-3 and other unsaturated fatty acids, in addition to prebiotics and probiotics, are under active investigation for their roles in gut health and immune regulation. Notably, plant-derived compounds, i.e.,

Indexed as

Dietary SupplementsPhytochemicalsVitiligoAntioxidantsHumansAntioxidantsPhytochemicalsautoimmune diseaseconvergence theorydietherbal medicinemacronutrientsmicronutrientsnatural productsnutritionphytochemicalsplant-derived productssupplementationvitaminsvitiligo

Identifiers

PMID39861486
PMCPMC11767946

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.