Evidence map›Paper›PMID 39861483›Full record

ArticleNutrients2025

Gluten-Free Diet and Health-Related Quality of Life: The Validated Hellenic Version of the Celiac Dietary Adherence Test.

Emmanuel Psylinakis, Alexios Manidis, Fotios Makris, Nikolaos Thalassinos, Anastasia Markaki, Vasileia Kounelaki, Eirini Sfakianaki, Aspasia Spyridaki

Abstract readValidation Study
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emmanuel PsylinakisDepartment of Nutrition and Dietetics Sciences, Hellenic Mediterranean University (HMU), Trypitos Area, 72300 Sitia, Greece.
Alexios ManidisDepartment of Nutrition and Dietetics Sciences, Hellenic Mediterranean University (HMU), Trypitos Area, 72300 Sitia, Greece.
Fotios MakrisDepartment of Nutrition and Dietetics Sciences, Hellenic Mediterranean University (HMU), Trypitos Area, 72300 Sitia, Greece.
Nikolaos ThalassinosDepartment of Nutrition and Dietetics Sciences, Hellenic Mediterranean University (HMU), Trypitos Area, 72300 Sitia, Greece.
Anastasia MarkakiDepartment of Nutrition and Dietetics Sciences, Hellenic Mediterranean University (HMU), Trypitos Area, 72300 Sitia, Greece.ORCID 0000-0001-8125-3015
Vasileia KounelakiDepartment of Nutrition and Dietetics Sciences, Hellenic Mediterranean University (HMU), Trypitos Area, 72300 Sitia, Greece.
Eirini SfakianakiDepartment of Nutrition and Dietetics Sciences, Hellenic Mediterranean University (HMU), Trypitos Area, 72300 Sitia, Greece.
Aspasia SpyridakiDepartment of Nutrition and Dietetics Sciences, Hellenic Mediterranean University (HMU), Trypitos Area, 72300 Sitia, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesA reliable assessment of gluten-free diet (GFD) adherence is essential for managing celiac disease (CD). This study aimed to validate the Hellenic version of the Celiac Disease Adherence Test (H-CDAT) to evaluate adherence levels and explore the impact of dietary adherence on health-related quality of life (HRQoL)-both of which have never been objectively assessed in Greek CD patients.

methodsThe study included 102 adult CD patients who completed H-CDAT, diet-related questions, and the 36-Item Short Form Health Survey (SF-36).

resultsH-CDAT demonstrated good psychometric properties and showed multiple strong correlations with HRQoL dimensions. H-CDAT adherence was Good in 38.2%, Moderate in 42.2%, and Poor in 19.6% of patients, despite their perception of effective adherence, with 51% never having visited a dietitian for guidance on a GFD. Patients scored significantly lower across most HRQoL dimensions compared to the general Greek population. When stratified into the three adherence categories, striking differences emerged between Good and Moderate adherence across both physical and mental health domains, highlighting that moderate adherence is not sufficient for optimal health outcomes.

conclusionsThese findings emphasize the critical role of strict GFD adherence in improving overall health and underscore the importance of dietetic intervention for achieving optimal patient outcomes.

Indexed as

Celiac DiseaseDiet, Gluten-FreePatient ComplianceQuality of LifeAdultAgedFemaleGreeceHumansMaleMiddle AgedPsychometricsReproducibility of ResultsSurveys and QuestionnairesYoung Adultceliac dietary adherence testceliac diseasedietary adherencegluten-free diethealth-related quality of lifenutritionvalidation

Identifiers

PMID39861483
PMCPMC11768578

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.