Evidence map›Paper›PMID 39861457›Full record

Trial reportNutrients2025

The Improvement Effects of

Jie Zhang, Cheng Li, Mengyao Duan, Zhen Qu, Yi Wang, Yao Dong, Ying Wu, Shuguang Fang, Shaobin Gu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Nutrients · 2026
    Article
  5. Review
  6. Review
  7. Antioxidants (Basel, Switzerland) · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jie ZhangCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471000, China.ORCID 0000-0002-2206-5126
Cheng LiCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471000, China.
Mengyao DuanCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471000, China.
Zhen QuCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471000, China.
Yi WangCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471000, China.
Yao DongDepartment of Research and Development, Wecare Probiotics Co., Ltd., Suzhou 215200, China.
Ying WuCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471000, China.
Shuguang FangDepartment of Research and Development, Wecare Probiotics Co., Ltd., Suzhou 215200, China.
Shaobin GuCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471000, China.

Funding

Key R&D Projects in Henan Province 221111111400Key R&D Projects in Henan Province 241111314200Major Science and Technology Special Projects in Henan Province 231100310200
6 · The paper itself

Abstract

BACKGROUND/

objectivesWith the improvement of living standards, alcoholic liver disease caused by long-term drinking has been a common multiple disease. Probiotic interventions may help mitigate liver damage caused by alcohol intake, but the mechanisms need more investigation.

methodsThis study involved 70 long-term alcohol drinkers (18-65 years old, alcohol consumption ≥20 g/day, lasting for more than one year) who were randomly assigned to either the BC99 group or the placebo group. Two groups were given BC99 (3 g/day, 1 × 10

resultsThe results showed that intervention with

conclusionsThese findings demonstrate that

Indexed as

Alcohol DrinkingEubacterialesGastrointestinal MicrobiomeLiverLiver Diseases, AlcoholicProbioticsAdolescentAdultAgedDouble-Blind MethodFemaleHumansLiver Function TestsMaleMiddle AgedYoung Adultalcoholic liver injurygut microbiotaoxidative stressrandomized controlled trialWeizmannia coagulans BC99

Identifiers

PMID39861457
PMCPMC11769147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.