Evidence map›Paper›PMID 39861366›Full record

ArticleNutrients2025

The Association Between Metabolic Score for Visceral Fat and Cognitive Function Among Older Adults in the United States.

Murong Cheng, Yuchi Meng, Zhenxue Song, Ling Zhang, Yuanjun Zeng, Dongfeng Zhang, Suyun Li

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Murong ChengDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, Qingdao 266071, China.
Yuchi MengDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, Qingdao 266071, China.
Zhenxue SongDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, Qingdao 266071, China.
Ling ZhangDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, Qingdao 266071, China.
Yuanjun ZengDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, Qingdao 266071, China.
Dongfeng ZhangDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, Qingdao 266071, China.ORCID 0000-0001-9308-9371
Suyun LiDepartment of Epidemiology and Health Statistics, School of Public Health, Qingdao University, Qingdao 266071, China.

Funding

National Natural Science Foundation of China 82003535Natural Science Foundation of Shandong Province ZR2020QH300
6 · The paper itself

Abstract

backgroundAlthough several studies have demonstrated a link between obesity and cognitive function, the majority have primarily utilized body mass index (BMI) and waist circumference, ignoring the distribution of body fat. Evidence regarding the association of metabolic score for visceral fat (METS-VF), a proposed measurement for visceral adipose tissue (VAT), with cognitive function remains limited. We mainly aimed to investigate this association in older adults in the United States. METHODOLOGY: Data were from the National Health and Nutrition Examination Survey (NHANES) 2011 to 2014. Weighted linear regression models were adopted to examine the association of METS-VF and cognitive function scores, with further exploration of these associations across different obesity subgroups. Smoothing curve analysis, along with threshold and saturation effect analysis, were conducted to explore potential non-linear relationships.

resultsIn the multivariable-adjusted model, participants in the highest quartile (Quartile 4) of METS-VF exhibited a β coefficient of -1.52 [95% CI (-2.43, -0.62)] for the CERAD score compared with those in the lowest quartile (Quartile 1). Threshold and saturation effect analysis revealed non-linear associations of METS-VF with DSST score and Z-score.

conclusionsThe findings of this study indicate that elevated METS-VF scores are inversely related to cognitive function, highlighting the importance of considering visceral fat distribution in cognitive health assessments.

Indexed as

CognitionIntra-Abdominal FatMetabolic SyndromeAgedBody Mass IndexCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysObesityUnited StatesWaist CircumferenceBMIcognitive functionMETS-VFNHANESvisceral adipose tissue

Identifiers

PMID39861366
PMCPMC11768000

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.