Evidence map›Paper›PMID 39861354›Full record

ArticleNutrients2025

The Application of Olive-Derived Polyphenols on Exercise-Induced Inflammation: A Scoping Review.

Joseph B Lillis, Ashley G B Willmott, Havovi Chichger, Justin D Roberts

Abstract readScoping Review
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joseph B LillisCambridge Centre for Sport and Exercise Sciences (CCSES), Faculty of Science and Engineering, Anglia Ruskin University, Cambridge CB1 1PT, UK.
Ashley G B WillmottCambridge Centre for Sport and Exercise Sciences (CCSES), Faculty of Science and Engineering, Anglia Ruskin University, Cambridge CB1 1PT, UK.ORCID 0000-0001-7322-2569
Havovi ChichgerSchool of Life Sciences, Faculty of Science and Engineering, Anglia Ruskin University, Cambridge CB1 1PT, UK.ORCID 0000-0002-8549-7583
Justin D RobertsCambridge Centre for Sport and Exercise Sciences (CCSES), Faculty of Science and Engineering, Anglia Ruskin University, Cambridge CB1 1PT, UK.ORCID 0000-0002-3169-2041

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThere is current scientific interest pertaining to the therapeutic effects of olive-derived polyphenols (ODPs), in particular their associated anti-inflammatory properties, following the wealth of research surrounding the physiological impact of the Mediterranean Diet (MD). Despite this association, the majority of the current literature investigates ODPs in conjunction with metabolic diseases. There is limited research focusing on ODPs and acute inflammation following exercise, regardless of the knowledge surrounding the elevated inflammatory response during this time. Therefore, the aim of this scoping review is to understand the impact ODPs may have on exercise-induced inflammation.

methodsThis scoping review was undertaken in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScRs). The literature searches were conducted in PubMed and EBSCOhost and considered for review if records reported original data, examined olives, olive-derived nutrients, food sources, or ODPs in conjunction with exercise-induced inflammation (including known causes, associations, and proxy measures).

resultsSeven studies investigated ODPs and exercise-induced inflammation, providing commentary on reduced oxidative stress, inflammatory biomarkers, and immune biomarkers, enhanced antioxidant defenses and modulations in mitochondrial function, albeit in low numbers. An average of 100.9 mg∙d

conclusionsThere is a limited consensus on the direction of isolated HT in human models, whereas animal models suggest a reduced inflammatory response following ≥2 weeks HT supplementation in conjunction with chronic exercise. Future research should initially investigate the inflammatory response of ODP, with particular focus on HT, and aim to identify an optimum dose and time course for supplementation surrounding exercise to support acute recovery and exercise adaptations.

Indexed as

Anti-Inflammatory AgentsExerciseInflammationOleaPolyphenolsAnimalsAntioxidantsDietary SupplementsDiet, MediterraneanHumansOxidative StressAnti-Inflammatory AgentsAntioxidantsPolyphenolsexercisehydroxytyrosolinflammationolivespolyphenols

Identifiers

PMID39861354
PMCPMC11767577

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.