Evidence map›Paper›PMID 39861341›Full record

ReviewNutrients2025

Postprandial Aminoacidemia Following the Ingestion of Alternative and Sustainable Proteins in Humans: A Narrative Review.

Mohammed Ahmed Yimam, Martina Andreini, Sara Carnevale, Maurizio Muscaritoli

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammed Ahmed YimamDepartment of Science, Technology and Society, University School for Advanced Studies IUSS Pavia, 27100 Pavia, Italy.ORCID 0000-0003-1567-1571
Martina AndreiniDepartment of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.
Sara CarnevaleBelcolle Hospital, 01100 Viterbo, Italy.
Maurizio MuscaritoliDepartment of Translational and Precision Medicine, Sapienza University of Rome, 00185 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a pressing need to expand the production and consumption of alternative protein sources from plants, fungi, insects, and algae from both nutritional and sustainability perspectives. It is well known that the postprandial rise in plasma amino acid concentrations and subsequent muscle anabolic response is greater after the ingestion of animal-derived protein sources, such as dairy, meat, and eggs, than plant-based proteins. However, emerging evidence shows that a similar muscle anabolic response is observed-despite a lower and slower postprandial aminoacidemia-after the ingestion of alternative protein sources compared with animal-derived protein sources. Therefore, a comprehensive analysis of plasma amino acid kinetics after the ingestion of alternative protein sources would play a significant role in recognizing and identifying the anabolic properties of these protein sources, allowing for the implementation of the best nutritional intervention strategies, contributing to more sustainable food production, and developing new medical nutritional products with optimal impacts on muscle mass, strength, and function, both in terms of health and disease. Therefore, this narrative review is focused on postprandial amino acid kinetics (the area under the curve, peak, and time to reach the peak concentration of amino acids) based on experimental randomized controlled trials performed in young and older adults following the ingestion of different novel, sustainable, and alternative protein sources.

Indexed as

Amino AcidsDietary ProteinsPostprandial PeriodAnimalsHumansAmino AcidsDietary Proteinsagingalgae-derivedalternative protein sourcesaminoacidemiachronic diseasesfungi-derivedinsect-derivedplant-derivedsarcopeniasustainability

Identifiers

PMID39861341
PMCPMC11767605

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.