Evidence map›Paper›PMID 39861306›Full record

ArticlePolymers2025

Microbial Adhesion and Cytotoxicity of Heat-Polymerized and 3D-Printed Denture Base Materials when Modified with Dimethylaminohexadecyl Methacrylate and/or 2-Methacryloyloxyethyl Phosphorylcholine as Antimicrobial and Protein-Repellent Materials.

Njood F AlAzzam, Salwa O Bajunaid, Bashayer H Baras, Heba A Mitwalli, Michael D Weir, Hockin H K Xu

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Njood F AlAzzamDepartment of Prosthetic Sciences, College of Dentistry, King Saud University, Riyadh 60169-15, Saudi Arabia.
Salwa O BajunaidDepartment of Prosthetic Sciences, College of Dentistry, King Saud University, Riyadh 60169-15, Saudi Arabia.
Bashayer H BarasDepartment of Restorative Dental Sciences, College of Dentistry, King Saud University, Riyadh 60169-15, Saudi Arabia.
Heba A MitwalliDepartment of Restorative Dental Sciences, College of Dentistry, King Saud University, Riyadh 60169-15, Saudi Arabia.ORCID 0000-0003-3877-6632
Michael D WeirDepartment of Advanced Oral Sciences and Therapeutics, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.
Hockin H K XuDepartment of Advanced Oral Sciences and Therapeutics, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.

Funding

Saudi National Institute of Health SNIH- RO-HRT01-2302-KSU-36584095
6 · The paper itself

Abstract

backgroundPolymethyl methacrylate (PMMA) is ideal for denture bases but is prone to biofilm accumulation, leading to denture stomatitis (DS), often involving

methodsHP and 3DP denture base specimens were prepared using varying concentrations of DMAHDM and MPC. Microbial adhesion was quantified using CFU counts of

resultsBoth DMAHDM and MPC significantly reduced the CFU counts in both HP and 3DP materials; the combination of 1.5% DMAHDM and 3% MPC exhibited the most substantial antimicrobial effects. Cytotoxicity results varied between materials and time points; however, all treated groups maintained cell viability above the 70% threshold, indicating no significant cytotoxic effects.

conclusionIncorporating DMAHDM and MPC into denture base resins can effectively reduce microbial adhesion while maintaining acceptable cytotoxicity levels.

Indexed as

antimicrobialcytotoxicitydenture basemicrobial adhesionprotein-repellent

Identifiers

PMID39861306
PMCPMC11768527

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.