Evidence map›Paper›PMID 39861293›Full record

ArticlePolymers2025

A Preliminary Stability Assessment of Three State-of-the-Art CAD/CAM Materials Under Human Gingival Cell Culture.

Eduard Gatin, Stefan Iordache, Ana Maria Iordache, Alexandra Totan Ripsvki, Antoniu Moldovan, Catalin Luculescu

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eduard GatinFaculty of Medicine, University of Medicine ''Carol Davila'', 050474 Bucharest, Romania.
Stefan IordacheOptospintronics Department, National Institute for Research and Development in Optoelectronics-INOE 2000, 077125 Magurele, Romania.ORCID 0000-0002-9840-9896
Ana Maria IordacheOptospintronics Department, National Institute for Research and Development in Optoelectronics-INOE 2000, 077125 Magurele, Romania.ORCID 0000-0003-4705-0606
Alexandra Totan RipsvkiFaculty of Dentistry, University of Medicine "Carol Davila", 050474 Bucharest, Romania.ORCID 0000-0002-4345-282X
Antoniu MoldovanPlasma and Radiation Physics, National Institute for Laser, 077125 Magurele, Romania.ORCID 0000-0001-7953-9268
Catalin LuculescuPlasma and Radiation Physics, National Institute for Laser, 077125 Magurele, Romania.ORCID 0000-0001-6852-401X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CAM/CAD composites are widely used as dental restoration materials due to their resistivity to wear. The purpose of this study was to determine the effect of human gingival fibroblast cells on three different computer-aided design/computer-aided manufacturing (CAD/CAM) hybrid materials with resin-based composites (RBC) and to assess their stability following cell growth. The CAM/CAD dental materials were investigated in different conditions as follows: (i) cells (human gingival fibroblasts, HFIB-Gs) incubated over the material for each sample, denoted as A; (ii) reference, the raw material, denoted as B; and (iii) materials incubated in DMEM medium, denoted as C. We employed Vicker's hardness test, EDS, SEM, and AFM measurements as well as Raman spectroscopy to carefully characterize the surface modifications and the structural integrity of the CAM/CAD materials before and after fibroblast cell culture. The analysis of the surface in terms of morphology, roughness, structure, and plastic deformation presented no significant difference after incubation in cells or in media, proving their extraordinary stability and resilience to biofilm formation.

Indexed as

CAD/CAM materialscell cultureRaman spectroscopystructural integritysurface modificationsVicker’s hardness test

Identifiers

PMID39861293
PMCPMC11769571

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.