Evidence map›Paper›PMID 39861281›Full record

ArticlePolymers2025

Improved Biomineralization Using Cellulose Acetate/Magnetic Nanoparticles Composite Membranes.

Madalina Oprea, Andreea Madalina Pandele, Aurelia Cristina Nechifor, Adrian Ionut Nicoara, Iulian Vasile Antoniac, Augustin Semenescu, Stefan Ioan Voicu, Catalin Ionel Enachescu, Anca Maria Fratila

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Magnetic Hydrogels as a Treatment for Oncological Pathologies.Journal of functional biomaterials · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Madalina OpreaAdvanced Polymers Materials Group, National University of Science and Technology POLITEHNICA Bucharest, 1-7 Gheorghe Polizu, 011061 Bucharest, Romania.
Andreea Madalina PandeleAdvanced Polymers Materials Group, National University of Science and Technology POLITEHNICA Bucharest, 1-7 Gheorghe Polizu, 011061 Bucharest, Romania.
Aurelia Cristina NechiforDepartment of Analytical Chemistry and Environmental Engineering, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology POLITEHNICA Bucharest, 1-7 Gheorghe Polizu, 011061 Bucharest, Romania.ORCID 0000-0001-8891-8948
Adrian Ionut NicoaraDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology POLITEHNICA Bucharest, 1-7 Gheorghe Polizu, 011061 Bucharest, Romania.ORCID 0000-0002-4133-7377
Iulian Vasile AntoniacFaculty of Materials Science and Engineering, National University of Science and Technology POLITEHNICA Bucharest, 313 Splaiul Independentei, 060042 Bucharest, Romania.ORCID 0000-0003-0112-3494
Augustin SemenescuFaculty of Materials Science and Engineering, National University of Science and Technology POLITEHNICA Bucharest, 313 Splaiul Independentei, 060042 Bucharest, Romania.ORCID 0000-0001-6864-3297
Stefan Ioan VoicuAdvanced Polymers Materials Group, National University of Science and Technology POLITEHNICA Bucharest, 1-7 Gheorghe Polizu, 011061 Bucharest, Romania.ORCID 0000-0001-7191-7471
Catalin Ionel EnachescuDepartment of Dermatology, Elias Emergency University Hospital, 17 Bulevardul Marasti, 011461 Bucharest, Romania.
Anca Maria FratilaDepartment of Dental Medicine and Nursing, Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.ORCID 0000-0003-2217-6755

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following implantation, infections, inflammatory reactions, corrosion, mismatches in the elastic modulus, stress shielding and excessive wear are the most frequent reasons for orthopedic implant failure. Natural polymer-based coatings showed especially good results in achieving better cell attachment, growth and tissue-implant integration, and it was found that the inclusions of nanosized fillers in the coating structure improves biomineralization and consequently implant osseointegration, as the nanoparticles represent calcium phosphate nucleation centers and lead to the deposition of highly organized hydroxyapatite crystallites on the implant surface. In this study, magnetic nanoparticles synthesized by the co-precipitation method were used for the preparation of cellulose acetate composite coatings through the phase-inversion method. The biomineralization ability of the membranes was tested through the Taguchi method, and it was found that nanostructured hydroxyapatite was formed at the surface of the composite membrane (with a higher organization degree and purity, and a Ca/P percentage closer to the one seen with stoichiometric hydroxyapatite, compared to the one deposited on neat cellulose acetate). The results obtained indicate a potential new application for magnetic nanoparticles in the field of orthopedics.

Indexed as

biomineralizationcellulose acetatecoatingmagnetic nanoparticles

Identifiers

PMID39861281
PMCPMC11768280

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.